NCT04083612CompletedPhase 4
Therapeutic Drug Monitoring of Ixekizumab in Psoriasis Patients
Evaluation of the Predictive Value of Early Serum Trough Concentrations and Anti-drug Antibodies of Ixekizumab and the Development of Concentration-response Curve of Ixekizumab for Psoriasis Patients
Source: ClinicalTrials.gov · Last updated 19 Sept 2024
Brief summary (registry, in English)
Biologics, such as ixekizumab, are currently the most effective treatment option for patients with moderate-to-severe psoriasis. But they are costly for health care systems and prescribed according to a 'one dose fits all' dosing regimen, leading to potential over- and undertreatment. Within this study the investigators aim to investigate the predictive value of early serum trough levels of ixekizumab and determine the therapeutic window of ixekizumab in psoriasis patients.
- Status (registry)
- Completed
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 49 (actual)
- First submitted
- 19 Jul 2019
- Start date
- 4 May 2020
- Primary completion date
- 31 Dec 2023
- Lead sponsor
- University Hospital, Ghent
- Diseases
- Psoriasis
- NCT number
- NCT04083612
What you commit to
- Study type: Interventional · Phase 4
- Participants enrolled: 49
- From 4 May 2020 to the primary completion date, 31 Dec 2023
- 7 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Participants who have currently a predominant nonplaque form of psoriasis
- Participants who are pregnant, nursing or planning a pregnancy
- Participants who are unable or unwilling to undergo multiple venapunctures
- Participants who are treated according to a different dosing schedule than standard dosing of ixekizumab
Who the study is looking for
- Participants must have a clinical or histological diagnosis of chronic plaque-type psoriasis
- Participants must sign an ICF indicating that he or she understands the purpose of, and procedures required for, the study and is willing to participate in the study
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (7)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| AZ Sint Jan Coordinator of this site? Confirm its status | Bruges | Belgium | Unknown status |
| AZ Maria Middelares Coordinator of this site? Confirm its status | Ghent | Belgium | Unknown status |
| AZ Sint-Lucas Coordinator of this site? Confirm its status | Ghent | Belgium | Unknown status |
| University Hospital of Ghent Coordinator of this site? Confirm its status | Ghent | Belgium | Unknown status |
| UZ Hospital Coordinator of this site? Confirm its status | Leuven | Belgium | Unknown status |
| Private Practice Dermatology Coordinator of this site? Confirm its status | Maldegem | Belgium | Unknown status |
| AZ Delta Rembert Coordinator of this site? Confirm its status | Torhout | Belgium | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.