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NCT04091464Completed

TRAIN-BW: Backward Walking Training in Multiple Sclerosis

Source: ClinicalTrials.gov · Last updated 19 Aug 2026

Brief summary (registry, in English)

Individuals with multiple sclerosis (MS) experience in impairments in mobility and cognition that increase the risk for accidental falls. More than 50% of individuals with MS experience injurious falls within a 6-month period. Current interventions to improve fall risk have focused on forward walking (FW) and balance training, resulting in small declines in the relative risk for falls with a large degree of variability. Interestingly, motor differences between MS and healthy controls are more pronounced in backward walking (BW), yet no studies have investigated BW training as an intervention to reduce fall risk in persons with MS. This study will investigate the feasibility, acceptability and impact of BW training compared to forward walking training on motor function and fall risk in persons with MS.

Status (registry)
Completed
Study type
Interventional
Enrollment
90 (actual)
First submitted
11 Sept 2019
Start date
1 Jan 2020
Primary completion date
30 May 2026
Lead sponsor
Wayne State University
NCT number
NCT04091464

What you commit to

  • Study type: Interventional
  • Participants enrolled: 90
  • From 1 Jan 2020 to the primary completion date, 30 May 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • comorbid neurological disorder
  • acute orthopedic disorder/injury

Other

  • MS relapse within the past 30 days
  • unable to follow study-related commands

Who the study is looking for

  • Diagnosis of MS
  • PDDS \<6, indicating ability to ambulate with or without an assistive device \>/= 50% of the time
  • Self-reported walking dysfunction as evidenced by a score of \>/= 30 on MSWS-12 OR reports of 2 or more falls in the prior 6 months, indicating a frequent faller.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Wayne State University
Coordinator of this site? Confirm its status
DetroitUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.