NCT04099992Completed
Mindfulness in Chronic Kidney Disease
Sympatho-inhibition With Mindfulness in Chronic Kidney Disease (MIND-CKD)
Source: ClinicalTrials.gov · Last updated 30 Oct 2026
Brief summary (registry, in English)
This study will test whether mindfulness meditation (MM) improves sympathetic function in chronic kidney disease (CKD) and whether transcutaneous vagus nerve stimulation (tVNS) optimizes the sympatho-inhibitory effects of mindfulness meditation (MM) and restores autonomic balance in CKD patients.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 151 (actual)
- First submitted
- 20 Sept 2019
- Start date
- 20 Sept 2019
- Primary completion date
- 7 May 2026
- Lead sponsor
- Emory University
- Diseases
- Chronic kidney disease
- NCT number
- NCT04099992
What you commit to
- Study type: Interventional
- Participants enrolled: 151
- From 20 Sept 2019 to the primary completion date, 7 May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- treatment with central α-agonists or monoamine oxidase (MAO) inhibitors
- ongoing drug or alcohol abuse (defined as \>2 drinks/day in men, and \>1 drink/day in women)
- surgery within the past 3 months
- adjustment of antihypertensive medications within the past month
- concurrent use of another stimulating device such as a transcutaneous electrical nerve stimulation (TENS) unit
Other illness
- any serious disease that might influence survival
- myocardial infarction or cerebrovascular accident within the past 6 months
- uncontrolled hypertension (BP≥170/100 mm Hg)
Lab values
- severe CKD (eGFR\<15 cc/min)
- anemia with hemoglobin \<10 g/dL
Other
- diabetic neuropathy
- autonomic dysfunction
- low BP (BP\<100/50 mm Hg)
- bradycardia (HR\<55 beats/min)
- pregnancy or plans to become pregnant
- psychosis
- suicidal ideation
- implanted electronic or metallic device such as a pacemaker
- implanted hearing aid, bone plate, carotid stent, bone screw at or near the neck
- carotid atherosclerosis
Who the study is looking for
- stages III and IV CKD as defined by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) creatinine equation
- stable renal function (no greater than a decline of eGFR of 1 cc/min/1.73 m2 per month over the prior 3 months)
Age in the registry: 40 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Atlanta VA Medical Center Coordinator of this site? Confirm its status | Atlanta | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.