NCT04107129Completed
Predicting Endometrial Receptivity for Optimal Reproductive Management
Predicting Endometrial Receptivity for Optimal Reproductive Management (PERFORM)
Source: ClinicalTrials.gov · Last updated 14 Aug 2024
Brief summary (registry, in English)
The purpose of this study is to understand why some women are infertile (unable to conceive a child). The investigators hope to learn if an endometrial biopsy after egg retrieval is feasible for detecting biomarkers for endometriosis and predicting implantation and pregnancy rate after embryo transfer. This study design will provide for the first time, an opportunity to compare endometrial biopsy material from hyperstimulated (gonadotropin treated) subjects after egg retrieval. If successful, it would provide a new protocol for women with unexplained infertility or those with known endometriosis to avoid poor IVF outcomes.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 76 (actual)
- First submitted
- 17 Sept 2019
- Start date
- Jul 2020
- Primary completion date
- Jul 2023
- Lead sponsor
- Stanford University
- Diseases
- Endometriosis
- NCT number
- NCT04107129
What you commit to
- Study type: Observational
- Participants enrolled: 76
- From Jul 2020 to the primary completion date, Jul 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Ovarian failure and subjects receiving donor oocytes/embryos
Other illness
- Polycystic ovary syndrome (PCOS) according with the Rotterdam criteria.
- Diabetes mellitus (Type I or Type II)
Other
- Uterine fibroids \> 4 cm in size
- Anti-cardiolipid and/or lupus anti-coagulant abnormalities by history
- Untreated hypothyroidism
- Hyperprolactinemia
- Uncorrected uterine anomaly
Who the study is looking for
- Age - 18 to 42
- AMH ≥ 1
- Planning to undergo IVF with delayed embryo transfer
- Must have blastocyst(s) by day 6 that were biopsied for PGT-A
- BMI 18-35
Age in the registry: 18 years to 42 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Stanford Fertility and Reproductive Health Coordinator of this site? Confirm its status | Sunnyvale | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.