NCT04109820Completed
Effect of MitoQ on Platelet Function and Reactive Oxygen Species Generation in Patients With Sickle Cell Anemia
Effect of MitoQ on Platelet Function and Reactive Oxygen Species (ROS) Generation in Patients With Sickle Cell Anemia
Source: ClinicalTrials.gov · Last updated 2 Sept 2026
Brief summary (registry, in English)
MitoQ is commercially available as a dietary supplement and it has been tested as a potential drug in other diseases, but it has never been tested in patients with sickle cell disease. The goal of this research is to study if MitoQ, a molecule that works as an antioxidant by removing potentially damaging agents in a living organism, improves platelet function in patients with sickle cell disease (SCD).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 18 (actual)
- First submitted
- 27 Aug 2019
- Start date
- 10 Mar 2020
- Primary completion date
- 27 Sept 2022
- Lead sponsor
- University of Pittsburgh
- Diseases
- Sickle cell disease
- NCT number
- NCT04109820
What you commit to
- Study type: Interventional
- Participants enrolled: 18
- From 10 Mar 2020 to the primary completion date, 27 Sept 2022
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known hypertension,
Lab values
- Use of anti-platelet medication or have had transfusion in the 4 weeks prior to enrollment.
Other
- Pregnancy,
- Hemodialysis and active obstructive sleep apnea requiring treatment.
Who the study is looking for
- Subjects
- African American
- Patients with sickle cell anemia
- 18 years old or older
- Control
- African American healthy controls
- 18 years of age or older
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Children's Hospital of Pittsburgh Coordinator of this site? Confirm its status | Pittsburgh | United States | Unknown status |
| Magee - Women's Hospital Coordinator of this site? Confirm its status | Pittsburgh | United States | Unknown status |
| UPMC Presbyterian Coordinator of this site? Confirm its status | Pittsburgh | United States | Unknown status |
| Hillman Cancer Center Coordinator of this site? Confirm its status | Pittsburgh | United States | Unknown status |
| UPMC Montefiore Coordinator of this site? Confirm its status | Pittsburgh | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.