NCT04110795Active, not recruiting
Personalizing Osteoporosis Care: Clinical & Genetic Risk Factors for AFFs
Personalizing Osteoporosis Care: Clinical & Genetic Risk Factors for Atypical Femur Fractures
Source: ClinicalTrials.gov · Last updated 11 May 2026
Brief summary (registry, in English)
The overall objective of this project is to identify clinical and genetic risk factors for Atypical Femur Fractures (AFFs) in Anti-resorptive therapy (ART) users by conducting a case control study of 330 cases of AFFs and 660 controls without AFFs matched for age, sex, race and duration of ART.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 1200 (estimated)
- First submitted
- 25 Sept 2019
- Start date
- 25 Jun 2018
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- University Health Network, Toronto
- Diseases
- Osteoporosis
- NCT number
- NCT04110795
What you commit to
- Study type: Observational
- Planned participants: 1200
- From 25 Jun 2018 to the primary completion date, 31 Dec 2027
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- \-
Who the study is looking for
- Cases: Have experienced a confirmed, documented Atypical femur fracture
- Controls: currently on anti-resorptive therapy, matches AFF case by age, race and length of ART use
Age in the registry: 18 years to - · Sex: Female · Accepts healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Adachi Medical Centre Coordinator of this site? Confirm its status | Hamilton | Canada | Unknown status |
| Bone Research & Education Centre Coordinator of this site? Confirm its status | Oakville | Canada | Unknown status |
| University Health Network/TGH Coordinator of this site? Confirm its status | Toronto | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.