NCT04119544Recruiting
Mirror Therapy Rehabilitation of the Upper Limb After Stroke (NEURO-MIROIR 2)
Intensive Rehabilitation Program With Intensive Visual Numerical Simulation Device for Improving Distal Motor Performance and Upper Limb Functional Capacity in Subacute Hemiparetics After Stroke. Randomized Controlled Trial.
Source: ClinicalTrials.gov · Last updated 18 Mar 2026
Brief summary (registry, in English)
Hemiparesis is a common motor disorder after a stroke. The majority of patients do not recover functional use of their paretic upper limb. The use of mirror therapy allows the activation of the mirror neurons involved to stimulate brain plasticity after brain damage.The IVS (Intensive Visual Stimulation) device allows an easy implementation of mirror therapy by filming the valid upper limb and projecting the inverted image onto a screen placed above the parietal arm thus producing the illusion of movement of the parietal arm. The main hypothesis of this study is that the structured practice of a large number of upper limb targeted movement repetitions using an intensive visual numerical simulation device as a partial replacement for routine care (conventional occupational therapy) in the sub-acute phase of stroke will increase the active function (motor function and functional abilities) of the distal end of the upper limb compared to conventional rehabilitation. Objectives: This randomized controlled trial will evaluate the effects of partial substitution of routine care (occupational therapy) by structured movement repetition programs by Intensive Visual Simulation using an IVS3 device, on the distal motor control of the upper hemiparesis limb, between 4 and 10 weeks after the stroke, compared to a program with conventional care alone.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 66 (estimated)
- First submitted
- 7 Oct 2019
- Start date
- 10 Dec 2019
- Primary completion date
- 31 Jul 2027
- Lead sponsor
- Clinique Les Trois Soleils
- Diseases
- Stroke
- NCT number
- NCT04119544
What you commit to
- Study type: Interventional
- Planned participants: 66
- From 10 Dec 2019 to the primary completion date, 31 Jul 2027
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Neurological conditions prior to stroke
- Patient who had mirror therapy or IVS rehabilitation before inclusion
Other illness
- Cognitive dysfunction or progressive intercurrent illness making effective communication or participation in the study impossible
- Phasic disorders that prevent the understanding of instructions
Other
- Patient include in an other clinical trial
- Rheumatological pathology of the hand and wrist
- Person under legal protection measure.
Who the study is looking for
- Age ≥18 years;
- Stroke hemiparesis on unilateral focal lesion dating from 4 to 10 weeks at baseline;
- Total sub-scores wrist and hand of th Fugl-Meyer \< 16
- Patient having agreed to sign an informed consent
- patient being affiliated to the French Social Security
Age in the registry: 18 years to 100 years · Sex: All · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Clinique Les Trois Soleils Coordinator of this site? Confirm its status | Boissise-le-Roi | France | Recruiting |
| CRF Pasori Coordinator of this site? Confirm its status | Cosne-Cours-sur-Loire | France | Recruiting |
| CHU Sébastopol Coordinator of this site? Confirm its status | Reims | France | Not yet recruiting |
| Clinique Napoléon Coordinator of this site? Confirm its status | Saint-Paul-lès-Dax | France | Not yet recruiting |
| Clinalliance Villiers-sur Orge Coordinator of this site? Confirm its status | Villiers-sur-Orge | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.