NCT04123197Completed
Mental Stress and Myocardial Ischemia After MI: Sex Differences, Mechanisms and Prognosis
Source: ClinicalTrials.gov · Last updated 24 Jul 2026
Brief summary (registry, in English)
The purpose of this study is to look at the link between emotional stress and heart disease in men and women. Taking part in this study involves one clinic visit, one week of at home monitoring, and follow up phone calls every 6 months for 3 years.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 306 (actual)
- First submitted
- 9 Oct 2019
- Start date
- 28 Feb 2020
- Primary completion date
- 31 May 2025
- Lead sponsor
- Emory University
- Diseases
- Coronary artery disease
- NCT number
- NCT04123197
What you commit to
- Study type: Interventional
- Participants enrolled: 306
- From 28 Feb 2020 to the primary completion date, 31 May 2025
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients deemed to be unsafe to hold anti-ischemic medications before testing (it is standard protocol to hold these meds before imaging studies)
- Postmenopausal hormone therapy (past 3 months)
- Current psychotropic medications (past month) except anti-depressants
Other illness
- History of unstable angina, MI, or decompensated heart failure in the past month
- Alcohol or substance abuse (past year), or severe psychiatric disorder other than major depression
- Other serious medical disorders that may interfere with the study results
Other
- Systolic blood pressure (SBP) \>180 mm Hg or diastolic blood pressure (DBP) \>110 mm Hg on the day of the test
- Pregnancy or breastfeeding (all women will receive a pregnancy test)
- Severe aortic stenosis
- Weight ≥ 360 pounds and/or body mass index (BMI) of 40 or greater (weight limit of the SPECT imaging table)
Who the study is looking for
- History of documented MI within the past 8 months
- Age ≤60 at the time of MI
Age in the registry: 18 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Grady Health System Coordinator of this site? Confirm its status | Atlanta | United States | Unknown status |
| The Emory Clinic Coordinator of this site? Confirm its status | Atlanta | United States | Unknown status |
| Emory University Hospital Coordinator of this site? Confirm its status | Atlanta | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.