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NCT04126616Completed

Pulmonary Vascular Impairment in Chronic Obstructive Pulmonary Disease (COPD) Assessed by MRI

Source: ClinicalTrials.gov · Last updated 19 Nov 2025

Brief summary (registry, in English)

Chronic Obstructive Pulmonary Disease (COPD) is a highly prevalent pulmonary disease providing major morbidity and mortality. Bronchial obstruction is the cornerstone in assessment of the disease whereas associated pulmonary vascular disease remains poorly known. Improving knowledge on pulmonary vascular adaptive skills in COPD patients could allow for better understanding disease exacerbations, evolution towards chronic pulmonary hypertension (PH) and therapeutics to be offered to the patients. Magnetic resonance imaging (MRI) is an innovative and non-invasive tool capable of pulmonary vascular evaluation. This work aims at identifying pulmonary vascular impairment in COPD patients using functional MRI.

Status (registry)
Completed
Study type
Interventional
Enrollment
30 (actual)
First submitted
9 Oct 2019
Start date
15 Oct 2019
Primary completion date
15 Oct 2025
Lead sponsor
Assistance Publique Hopitaux De Marseille
Diseases
COPD
NCT number
NCT04126616

What you commit to

  • Study type: Interventional
  • Participants enrolled: 30
  • From 15 Oct 2019 to the primary completion date, 15 Oct 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • side effect for exercise
  • side effect for MRI and contrast agent injection
  • Pregnancy or breastfeeding
  • Refusing to be informed of the discovery of an anomaly on chest MRI

Who the study is looking for

  • Age 40-70
  • Diagnosed with COPD
  • Emphysema on chest CT
  • FEV1 between 35 and 80 %
  • Screened for PH by echocardiography

Age in the registry: 40 years to 70 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Assistance Publique Hôpitaux de Marseille
Coordinator of this site? Confirm its status
MarseilleFranceUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.