NCT04137523Completed
Investigate eNAMPT in Multiple Myeloma Biology and Establish Its Role in Disease Progression
INVESTIGATING eNAMPT ROLE IN ACQUISITION OF EPITHELIAL TO MESENCHYMAL TRANSITION-LIKE FEATURES IN MULTIPLE MYELOMA
Source: ClinicalTrials.gov · Last updated 11 Dec 2024
Brief summary (registry, in English)
Based on our previous observations, here the investigator plans to further investigate eNAMPT in MM biology and to establish its role in disease progression where EMT acquisition represents an hallmark of cancers. Results deriving from proposal would hopefully identify novel biological vulnerabilities of such malignancy and an innovative biomarker for disease progression monitoring as well.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 26 (actual)
- First submitted
- 21 Oct 2019
- Start date
- 12 Aug 2019
- Primary completion date
- 12 Aug 2019
- Lead sponsor
- University of Turin, Italy
- Diseases
- Multiple myeloma
- NCT number
- NCT04137523
What you commit to
- Study type: Observational
- Participants enrolled: 26
- From 12 Aug 2019 to the primary completion date, 12 Aug 2019
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- Male and female patients over 18 years of age;
- PB-derived serum samples collected in different disease phases (MGUS, SMM, NDMM and RRMM MM patients)
- Sufficient CD138+ cells or RNA from CD138+ cells are available;
- ≥ 2 years median survival data and treatment data is available (progression free and overall survival);
- Bone marrow sample acquired prior to the initiation of the therapy of interest;
- Patients have consented for use of their sample for research purposes.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| AOU Città della Salute e della Scienza di Torino Coordinator of this site? Confirm its status | Torino | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.