NCT04138030Completed
Conventional Endoscopic Mucosal Resection Versus Cold Snare Endoscopic Mucosal Resection of Colonic Lateral Spreading Lesions - A Randomised Controlled Trial
Conventional Versus Cold Snare Endoscopic Mucosal Resection of Colonic Lateral Spreading Lesions - A Randomised Controlled Trial
Source: ClinicalTrials.gov · Last updated 27 Mar 2025
Brief summary (registry, in English)
Comparing the complete resection rate and subsequent adenoma recurrence rate at surveillance colonoscopy of 15-40mm laterally spreading adenomas for conventional EMR vs. cold snare EMR.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 182 (actual)
- First submitted
- 20 Oct 2019
- Start date
- 12 Nov 2019
- Primary completion date
- 5 Mar 2024
- Lead sponsor
- Western Sydney Local Health District
- Diseases
- Colorectal cancer
- NCT number
- NCT04138030
What you commit to
- Study type: Interventional
- Participants enrolled: 182
- From 12 Nov 2019 to the primary completion date, 5 Mar 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previously attempted or otherwise non-lifting lesions
- Endoscopic features suggestive of submucosal invasion (Kudo Vi/n, JNET 2b / 3) or concurrent CRC
Other illness
- Known bleeding disorder or coagulopathy.
- History of inflammatory bowel disease
Other
- Current use of antiplatelet (excluding aspirin) or anticoagulants which have not appropriately been interrupted according to the guidelines.
- Pregnancy
- Lesions involving the ileocaecal valve (ICV) or the anorectal junction (ARJ)
Who the study is looking for
- Any patient undergoing colonoscopy who is older than 18 years of age, has a written consent for trial participation and has at least one LSL meeting to the following description:
- Localisation in the colon or rectum
- Benign adenomatous surface features (Kudo III / IV, JNET 2a)
- Granular or non-granular topography
- Paris classification 0-IIa/IIb +/- Is
- If present, sessile component may be no greater than 10mm in size.
- Polyp size ranging from 15 to 40mm
Age in the registry: 18 years to 99 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Westmead Endoscopy Unit Coordinator of this site? Confirm its status | Westmead | Australia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.