NCT04138940Completed
Modulating Intensity and Dosage of Aphasia Scripts
Modulating Stimuli Intensity to Improve Clinical Outcomes in Aphasia Treatment
Source: ClinicalTrials.gov · Last updated 28 May 2025
Brief summary (registry, in English)
The purpose of this study is to evaluate how changing conditions of speech-language treatment (namely, amount of repetition and distribution of practice schedule) affects the language outcome of participants with aphasia following a stroke. Using a computer based speech and language therapy program, participants will practice conversational scripts that are either short or long. Participants will practice for either 2 weeks (5 days a week) or for 5 weeks (2 days a week).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 85 (actual)
- First submitted
- 23 Oct 2019
- Start date
- 21 Sept 2020
- Primary completion date
- 4 Dec 2024
- Lead sponsor
- Shirley Ryan AbilityLab
- Diseases
- Stroke
- NCT number
- NCT04138940
What you commit to
- Study type: Interventional
- Participants enrolled: 85
- From 21 Sept 2020 to the primary completion date, 4 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Any significant psychiatric history prior to the stroke, such as severe major depression or psychotic disorder requiring hospitalization; subjects with mood disorders who are currently stable on treatment will be considered
Other illness
- Any other neurological condition (other than cerebral vascular disease) that could potentially affect cognition or speech, such as Parkinson's Disease, Alzheimer's Dementia, traumatic brain injury
Other
- Active substance abuse
Who the study is looking for
- Men or women with diagnosis of aphasia
- Left-hemisphere stroke
- Aphasia Quotient score between 40-80 on the Western Aphasia Battery-Revised
- At least 6 months post stroke
- Completed at least eighth grade education
- Premorbidly literate in English
- Visual acuity no worse than 20/100 corrected in the better eye
- Auditory acuity no worse than 30 dB HL on pure tone testing, aided in better ear
- Not receiving speech-language therapy at the time of study
Age in the registry: 21 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Shirley Ryan AbilityLab Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.