NCT04140097Active, not recruiting
Predictors of Acute Exacerbation in Patients With COPD - an Observational Study
Predictors of Acute Exacerbation in Patients With COPD - an Observational Study (PACE Trial)
Source: ClinicalTrials.gov · Last updated 8 Nov 2024
Brief summary (registry, in English)
Chronic obstructive pulmonary disease (COPD) is a lung disease characterized by respiratory problems and poor airflow with dyspnea and cough being the main symptoms. Acute exacerbations of COPD (AECOPD) are the most important events for patients with COPD that have a negative impact on patients´ quality of life, accelerate disease progression, and can result in hospital admissions and death. It is of major clinical importance to determine predictors of an AECOPD and to identify patients who are at high risk for developing an acute exacerbation and/or to detect the beginning of or prevent an ongoing acute exacerbation as early as possible. Until now, research in the field of AECOPD has gathered and analyzed data only after manifestation of AECOPD until recovery and most of them used a retrospective study design. Therefore, the aim of this prospective trial is to collect clinical data in patients prior to the first visible clinical signs of an AECOPD to investigate potential early predictors of an AECOPD.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 355 (actual)
- First submitted
- 26 Sept 2019
- Start date
- 26 Feb 2020
- Primary completion date
- 30 Apr 2024
- Lead sponsor
- Schön Klinik Berchtesgadener Land
- Diseases
- COPD
- NCT number
- NCT04140097
What you commit to
- Study type: Observational
- Participants enrolled: 355
- From 26 Feb 2020 to the primary completion date, 30 Apr 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- \- current primary diagnosis of asthma
Who the study is looking for
- confirmed diagnosis of Chronic Obstructive Pulmonary Disease according to Global Association for Obstructive Lung Disease stage II to IV
- the ability to follow the rehabilitation protocol
- provided written informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Schoen Klinik Berchtesgadener Land Coordinator of this site? Confirm its status | Schönau am Königssee | Germany | Unknown status |
Related publications
- Timely management of COPD exacerbations is associated with limited acute deterioration and early recovery: a prospective observational study.Respir Res · 2026 · PMID 42432679
- Can Patient Education Lead the Way? Head-To-Head Comparison of EXACT and CERT for Early Recognition of Acute COPD Exacerbations.Respirology · 2026 · PMID 41320645
This page is information, not medical advice. Discuss any trial with your doctor.