NCT04142047Recruiting
Skeletal Muscle Energetics and Fatiguability in Older Individuals
Source: ClinicalTrials.gov · Last updated 8 Jun 2026
Brief summary (registry, in English)
The investigators are studying whether metabolic abnormalities in calf (leg) muscle in older people with and others without HIV are associated with decreased abilities to exercise.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 200 (estimated)
- First submitted
- 25 Oct 2019
- Start date
- 5 Sept 2019
- Primary completion date
- 1 Jul 2027
- Lead sponsor
- Johns Hopkins University
- Diseases
- HIV
- NCT number
- NCT04142047
What you commit to
- Study type: Observational
- Planned participants: 200
- From 5 Sept 2019 to the primary completion date, 1 Jul 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Significant cardiovascular, pulmonary or musculoskeletal or orthopedic disease that significantly limits exercise capacity
- Significant lower extremity peripheral vascular disease.
Other
- Unable to understand the risks, benefits, and alternatives of participation and give meaningful consent
- Contraindications to MRI
- Weight greater than 350 lbs
- Cognitive or speech impairments that would limit completion of questionnaires or fatigue reporting.
Who the study is looking for
- Participants who are \>= 60 years of age
- HIV serostatus positive participants on stable antiretroviral therapy (ART) (no regimen change in last month) with undetectable HIV viral load (\<100 copies).
- HIV serostatus negative participants
Age in the registry: 60 years to 90 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Johns Hopkins Hospital Coordinator of this site? Confirm its status | Baltimore | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.