NCT04142866Recruiting
Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia
Source: ClinicalTrials.gov · Last updated 7 Jan 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The purpose of this study is to assess changes in language abilities of participants with chronic, post-stroke aphasia following an 8-week therapy period combined with brain stimulation. The investigators use a stimulation method called transcranial direct current stimulation (tDCS). The investigators cover two electrodes in damp sponges, place them on the scalp, and pass a weak electrical current between them. Some of this current passes through the brain and can change brain activity. One electrode is placed over language areas a bit above and in front of the left ear. The other is placed on the forehead above the right eye. Stimulation is provided twice a week for 8 weeks during aphasia therapy. The investigators believe that this stimulation may increase the effectiveness of therapy.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 25 Oct 2019
- Start date
- 3 Jan 2025
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- City University of New York
- Diseases
- Stroke
- NCT number
- NCT04142866
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 3 Jan 2025 to the primary completion date, 31 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of seizure or change in seizure medication in past 12 months
- History of speech/language, psychiatric, or neurological disorder, or current serious medical condition (except chronic stroke comorbidities for participants with aphasia)
- Additional EXCLUSION criteria for participants with APHASIA are:
Other
- Failed vision or hearing screening
- MRI contraindications (including pacemaker)
- Pregnancy
- Unmodifiable hair style precluding scalp contact by electrodes
- Sensitive scalp by self-report
Who the study is looking for
- Right handed (pre-stroke for participants with aphasia)
- High school education or equivalent
- Native English fluency without early 2nd language exposure (before age 10)
- Ability to perform the required discourse and MRI tasks (determined via in-person screening)
- Additional INCLUSION Criteria for participants with APHASIA:
- Single-event left hemisphere stroke \> 6 months prior to enrollment
- Aphasia diagnosis per Western Aphasia Battery-Revised
- Not receiving any other speech therapy for the entire study period (20 weeks)
- Ability to perform the required therapy tasks (determined via in-person screening)
Criteria the registry did not label
- This study recruits individuals with post-stroke aphasia as well as a group of healthy volunteers matched for age, sex, and education.
Age in the registry: 21 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| City University of New York Coordinator of this site? Confirm its status | New York | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.