NCT04170062Completed
Oxygen Savings With Administered Oxygen and High Flow Ambient Air At Rest
Source: ClinicalTrials.gov · Last updated 24 Dec 2024
Brief summary (registry, in English)
This study is meant to compare the amount of oxygen required for hypoxemia relief between current standard of care (oxygen only) and oxygen with the addition of high flow air for Chronic Obstructive Pulmonary Disease (COPD), Interstitial Lung Disease (ILD), and Pulmonary Hypertension (PH) patients during rest. Subjects will be titrated from 0 L/min until they maintain 95% SpO2 for each of the following delivery methods: 1. Pulses of pure oxygen (control) 2. Constant high flow air with pulses of pure oxygen 3. Out of phase pulses of high flow air and pure oxygen
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 11 (actual)
- First submitted
- 18 Nov 2019
- Start date
- 15 Dec 2020
- Primary completion date
- 31 Dec 2023
- Lead sponsor
- Johns Hopkins University
- Diseases
- COPD
- NCT number
- NCT04170062
What you commit to
- Study type: Interventional
- Participants enrolled: 11
- From 15 Dec 2020 to the primary completion date, 31 Dec 2023
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Treatment with another investigational drug or other intervention within three months
Other illness
- Has any of the following: unstable angina, recent revascularization, recent history of cerebrovascular accident
Other
- Pregnancy or lactation
- Exacerbation that has resolved within the past 28 days
Who the study is looking for
- Provision of signed and dated informed consent form
- Stated willingness to comply with all study procedures and availability for the duration of the study
- Male or female, aged greater or equal to 30 years old
- Require Long Term Oxygen Therapy between 1 L/min and 4 L/min while at rest
- Have a peripheral blood saturation level above 80% with room air while seated
- Tolerate breathing while seated in room air
- Diagnosed with one of the following respiratory diseases: COPD (40% \< Forced Expiratory Volume (FEV1) \< 80% confirmed from pulmonary function test (PFT) within the last year), ILD (Confirmed with radiographic imaging), PH (Confirmed with radiographic imaging)
- Normal heart rate and blood pressure (Resting Heart Rate \<120 bpm, Systolic BP \<180 mmHg, Diastolic BP \<100mmHg)
- PFT taken in the last three months
Age in the registry: 30 years to 100 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Johns Hopkins Hospital Coordinator of this site? Confirm its status | Baltimore | United States | Unknown status |
| Johns Hopkins Hospital Bayview Asthma and Allergy Center Coordinator of this site? Confirm its status | Baltimore | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.