NCT04180267Terminated
RCT of Vibration Effect on Vertebral BMD in Disabled Patients
Efficacy of Low-magnitude High-frequency Vibration (LMHFV) on Musculoskeletal Health of Subjects on Wheelchair, a Randomized Controlled Study.
Source: ClinicalTrials.gov · Last updated 14 Feb 2025
Reason given: Discontinued due to COVID, community centres unable to provide services
Brief summary (registry, in English)
Osteoporosis is an age-related disease with progressive loss of bone, leading to fragile bone. It is one of the major health issues in elderly and causes medical, social and economic impacts globally. Patients with osteoporosis have high risk of osteoporotic fractures. Low-magnitude high-frequency vibration (LMHFV) is a non-invasive biophysical intervention providing whole-body mechanical stimulation. Previous studies showed that LMHFV is beneficial to muscle strength(1), postural control(2), balancing ability(3, 4), new bone formation(5-7), spinal bone mineral density (BMD)(8), and blood circulation(9). During the LMHFV treatment, elderly needs to stand upright on the platform for 20min/day. However, some elderlies with poor standing ability cannot stand for a long period. Therefore, the design of vibration platform is modified for the disabled patients and the efficacy of LMHFV on this group of elderlies will be verified. It is hypothesized that new design of LMHFV is beneficial to wheelchair users in terms of vertebral bone mineral density, muscle health and musculoskeletal functions.
- Status (registry)
- Terminated
- Study type
- Interventional
- Enrollment
- 37 (actual)
- First submitted
- 26 Nov 2019
- Start date
- 19 Jul 2019
- Primary completion date
- 8 Feb 2024
- Lead sponsor
- Chinese University of Hong Kong
- Diseases
- Osteoporosis
- NCT number
- NCT04180267
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Subjects with malignancy
- Subjects with chronic inflammatory conditions known to affect muscle metabolism such as rheumatoid arthritis
Other
- Subjects cannot stand and walk independently
- Subjects who had vibration treatment before
- Subjects with acute fractures or severe osteoarthritis
- Subjects with cardiovascular concern such as with pace-maker in-situ
- Subjects with high frequency of physical activities, such as subjects who participated in regular exercise five times a week or more
Who the study is looking for
- Subjects of both genders aged ≥ 65 years
- Wheelchair users with walking difficulties
- Subjects with good general health conditions
Age in the registry: 65 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Sun Chui Lutheran Centre For The Elderly | Hong Kong | Hong Kong | Unknown status |
| ELCHK, Shan King Care And Attention Home For The Elderly | Hong Kong | Hong Kong | Unknown status |
| Evangelical Lutheran Church Social Service - Hong Kong | Hong Kong | Hong Kong | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.