NCT04183218Completed
Characterizing Chemo-Radiotherapy Treatment-Related Cardiac Changes
Source: ClinicalTrials.gov · Last updated 27 May 2026
Brief summary (registry, in English)
This trial studies cardiac changes after radiation or chemo-radiation for the treatment of lung or esophageal cancer that has not spread to other places in the body (non-metastatic) or has not come back (non-recurrent). Continuous cardiac monitoring with an implanted device may help to identify cardiac changes that would remain unnoticed, and facilitate the treatment of these early cardiac changes as part of standard care.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 24 (actual)
- First submitted
- 27 Nov 2019
- Start date
- 23 Sept 2019
- Primary completion date
- 6 Jan 2024
- Lead sponsor
- Mayo Clinic
- Diseases
- Lung cancer, Gastric and esophageal cancer
- NCT number
- NCT04183218
What you commit to
- Study type: Observational
- Participants enrolled: 24
- From 23 Sept 2019 to the primary completion date, 6 Jan 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patient receiving radiation prescription doses lower than 40 Gy
- No prior radiation that included any part of the heart is acceptable
- No thoracic re-irradiation
Other illness
- Metastatic disease
- Recurrent disease
Who the study is looking for
- Age \>= 18 years
- Planned standard of care curative thoracic RT or CRT with anticipated heart V40 \> 20 cc (At least 20 cc of the heart should receive a dose of 40 gray \[Gy\] or higher)
- Able to follow-up at all specified standard of care time-points
- Patients can receive treatment as part of the standard of care or in a different study
- Receiving radiation treatment to an area close to the heart, for example gastroesophageal junction cancer, hilar lung cancer, or mainstem bronchus lung cancer
- Any type of systemic therapy or surgery before during or after radiation is acceptable
- Prior radiation to other areas is acceptable
- Planned radiation doses equal or higher than 40 Gy
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mayo Clinic in Arizona Coordinator of this site? Confirm its status | Scottsdale | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.