NCT04206436Active, not recruiting
CFTR Modulator Effects on Bone and Muscle in Adults With Cystic Fibrosis
Source: ClinicalTrials.gov · Last updated 2 Oct 2025
Brief summary (registry, in English)
Study is looking at the effects of cystic fibrosis treatment on bone muscle.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 63 (actual)
- First submitted
- 18 Dec 2019
- Start date
- 18 Dec 2019
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- Indiana University
- Diseases
- Cystic fibrosis
- NCT number
- NCT04206436
What you commit to
- Study type: Observational
- Participants enrolled: 63
- From 18 Dec 2019 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Lab values
- • Estimated glomerular filtration rate (eGFR) \<30 ml/min/m2 using the CKD-EPI equation,
- Treatment with any osteoporosis medication within 6 months for oral agents or 1 year for intravenous or injectable agents (Subjects may participate if therapy stopped earlier than these time periods).
- Current treatment with growth hormone or IGF-1
- Currently pregnant or lactating or planning plan on becoming pregnant during the duration of the study.
- Life expectancy less than 12 months
- History of lung transplantation
- Conditions that in the opinion of the investigators would interfere with the ability to collect or interpret the data, or put the patient at higher safety risk from study procedures.
Who the study is looking for
- documented, confirmed diagnosis of CF
- Age ≥18 years old
- \>21 days since the start of their last pulmonary exacerbation at the baseline visit
- Provide signed written informed consent to participate
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Indiana University Coordinator of this site? Confirm its status | Indianapolis | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.