NCT04215783Active, not recruiting
Childhood Allergy and the Neonatal Environment
Source: ClinicalTrials.gov · Last updated 11 Sept 2026
Brief summary (registry, in English)
The purpose of this research study is to study the relationship between childhood asthma, allergies, and early-life environmental factors that may cause childhood asthma and allergies. Previous birth cohort studies have found early-life environmental factors such as allergies, pollutants, viruses and bacteria have all contributed to the development of asthma and allergies. Investigators are doing this research because there continues to be a strong need to understand the root causes of asthma and allergies. The CANOE study is an observational cohort study, which means investigators are not asking participants or participant's child to change their medications and investigators will not be giving participants or participant's child a study drug.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 499 (actual)
- First submitted
- 30 Dec 2019
- Start date
- 4 Mar 2020
- Primary completion date
- 31 Aug 2027
- Lead sponsor
- University of Wisconsin, Madison
- Diseases
- Asthma
- NCT number
- NCT04215783
What you commit to
- Study type: Observational
- Participants enrolled: 499
- From 4 Mar 2020 to the primary completion date, 31 Aug 2027
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Current maternal use of progesterone during pregnancy to prevent preterm birth.
- Progesterone use is only an exclusion if currently being taken at time of enrollment for preterm birth. Previous use to prevent preterm birth or use at any time for other indications is allowed.
Other illness
- Maternal HIV infection at time of delivery.
Lab values
- Past or current medical problems or findings from physical examination or laboratory testing which, in the opinion of the investigator or designee, may pose additional risks from participation in the study, may interfere with the participant's ability to comply with study requirements or that may impact the quality or interpretation of the data obtained from the study.
Other
- Plans for the family to move out of the geographic area during the period of the study.
- Does not speak English.
- Pregnancy is a result of an embryo donor (egg and sperm donor pregnancies are permitted).
Who the study is looking for
- History of or concurrent asthma or allergic rhinitis (hay fever) in either biologic parent or sibling (at least one shared biological parent) by parental report. The presence of paternal or sibling allergy or asthma will be ascertained by maternal report.
- Maternal age greater than or equal to 18 years at the time of study enrollment.
Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Henry Ford Health Systems Coordinator of this site? Confirm its status | Detroit | United States | Unknown status |
| University of Wisconsin Coordinator of this site? Confirm its status | Madison | United States | Unknown status |
| Vanderbilt University Medical Center Coordinator of this site? Confirm its status | Nashville | United States | Unknown status |
| Washington University School of Medicine Coordinator of this site? Confirm its status | St Louis | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.