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NCT04217239Completed

A Comparison Between Ivor-Lewis and McKeown Minimally Invasive Esophagectomy

A Comparison of Short-term and Long- Term Outcomes Between Ivor-Lewis and McKeown Minimally Invasive Esophagectomy

Source: ClinicalTrials.gov · Last updated 5 Feb 2026

Brief summary (registry, in English)

Surgery is still the main treatment for esophageal cancer, however, the complication and mortality rate of open esophagectomy is high. As a result, the thoracoscopic- laparoscopic minimally invasive esophagectomy (MIE) was developed. The MIE mainly comprised two surgical approaches: MIE McKeown approach (cervical anastomosis) and MIE Ivor-Lewis approach (intrathoracicanastomosis). The MIE with intrathoracic anastomosis (Ivor-Lewis) is increasingly used for the treatment of mid and lower esophageal cancers. Our study is trying to compare the safety, feasibility, and short-term and long- term outcomes between MIE Ivor-Lewis approach and MIE McKeown approach for the treatment of lower thoracic esophageal cancer and esophageal- gastric junction.

Status (registry)
Completed
Study type
Interventional
Enrollment
272 (actual)
First submitted
1 Jan 2020
Start date
1 Jan 2020
Primary completion date
30 Jun 2024
Lead sponsor
The Second Hospital of Shandong University
NCT number
NCT04217239

What you commit to

  • Study type: Interventional
  • Participants enrolled: 272
  • From 1 Jan 2020 to the primary completion date, 30 Jun 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • (I) cardiopulmonary function not good enough for surgery;

Other

  • (II) Patients with hybrid MIE

Who the study is looking for

  • (I) Patients with clinically staged T1-3N0-2M0 tumors; good cardiopulmonary function;
  • (II) Patients with lower thoracic esophageal tumors and esophageal- gastric junction tumor;
  • (III) Patients without a previous history of cancer;
  • (IV) Patients without a previous history of neck or chest surgery;

Age in the registry: 30 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Yunpeng Zhao
Coordinator of this site? Confirm its status
JinanChinaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.