NCT04218903Completed
Resistance Plus Aerobic Training Using Different Weekly Frequencies And Hypertension
Comparison of Different Weekly Frequencies of Combined Training on Ambulatory Blood Pressure and Other Cardiovascular Risk Factors in Individuals With Hypertension: a Randomized Clinical Trial
Source: ClinicalTrials.gov · Last updated 24 Apr 2025
Brief summary (registry, in English)
Combined training is a cornerstone intervention to improve functionality and to reduce blood pressure in older adults with hypertension. Acute blood pressure lowering after exercise seems to predict the extent of blood pressure reduction after chronic training interventions. Based on that, the same weekly amount of exercise performed more frequently could be more beneficial to blood pressure management. The aim of the present study is to evaluate the effects of a combined exercise program performed four versus two times per week on 24-h ambulatory blood pressure and other cardiovascular risk factors in older individuals with hypertension.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 98 (actual)
- First submitted
- 3 Jan 2020
- Start date
- Mar 2022
- Primary completion date
- Dec 2024
- Lead sponsor
- Hospital de Clinicas de Porto Alegre
- Diseases
- High blood pressure
- NCT number
- NCT04218903
What you commit to
- Study type: Interventional
- Participants enrolled: 98
- From Mar 2022 to the primary completion date, Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Underlying cardiovascular disease in the last 24 months such as acute myocardial infarction, angina, stroke or heart failure
- Health conditions that limit physical exercise perform, such as lung disease, valvar heart disease, renal failure
- Diseases that reduce life expectancy
Other
- Physical and muscular injuries that limit to accomplishment of the different training proposed in the study
- BMI \> 39.9 kg/m²
- Diabetic proliferative retinopathy
Who the study is looking for
- Office blood pressure between 130-179 and 80-110 mmHg for systolic and diastolic blood pressure, respectively or taking at least one antihypertensive medication
- Not engaged in structured exercise programs (3 or more times per week) in the last 3 months before the study
Age in the registry: 50 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital de Clinicas de Porto Alegre Coordinator of this site? Confirm its status | Porto Alegre | Brazil | Unknown status |
Related publications
- Differential Effects of Twice vs. Four Times Weekly Combined Exercise Training in Aging Adults With Hypertension: A Randomized Clinical Trial.Scand J Med Sci Sports · 2026 · PMID 41792948
This page is information, not medical advice. Discuss any trial with your doctor.