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NCT04220047Recruiting

Effects of Left Atrial Appendage Resection and Marshall Ligament Amputation on Clinical Outcome in Patients Undergoing Off-pump Coronary Artery Bypass

Fuwai Hospital, Chinese Academy of Medical Science

Source: ClinicalTrials.gov · Last updated 20 Jan 2021 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

Surgical occlusion of the left atrial appendage (LAAO) is sometimes performed during the cardiac surgery to reduce long-term risk of stroke.A previous study found that LAAO may be associated with increased risk of postoperative atrial fibrillation.New-onset atrial fibrillation (NOAF) after coronary artery bypass graft is related to an increased short-term and long term risk of stroke and mortality.Marshall ligament amputation may reduce the occurence of atrial fibrillation. However, little is known whether this approach is justified during the coronary artery bypass graft.Therefore, this study aimed to investigate whether LAAO and Marshall ligament amputation during off-pump coronary artery bypass was associated with reduced risks of postoperative new-onset atrial fibrillation and stroke.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
400 (estimated)
First submitted
5 Jan 2020
Start date
30 Apr 2020
Primary completion date
31 Dec 2021
Lead sponsor
China National Center for Cardiovascular Diseases
NCT number
NCT04220047

What you commit to

  • Study type: Interventional
  • Planned participants: 400
  • From 30 Apr 2020 to the primary completion date, 31 Dec 2021
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Concurrent cardiac or non-cardiac surgery
  • Intraoperative convert to bypass bypass surgery
  • Emergency surgery
  • History of previous cardiac surgery

Other illness

  • Preoperative atrial fibrillation or a history of atrial fibrillation;

Other

  • Severe organ dysfunction

Who the study is looking for

  • isolated first off-pump coronary artery bypass

Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

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SiteCityCountrySite status
Fuwai Hospital
Coordinator of this site? Confirm its status
BeijingChinaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.