NCT04232566Recruiting
Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity
Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity- AIM 1
Source: ClinicalTrials.gov · Last updated 28 Jan 2026
Brief summary (registry, in English)
This study is being done to better understand the relationship between inflammation in adipose tissue (AT), abnormal deposition of fat around the liver and how this affects its appearance and function and ultimately insulin resistance.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 60 (estimated)
- First submitted
- 2 Jan 2019
- Start date
- 20 Feb 2022
- Primary completion date
- 31 Dec 2025
- Lead sponsor
- Mayo Clinic
- Diseases
- Obesity, Fatty liver disease (MASLD/MASH)
- NCT number
- NCT04232566
What you commit to
- Study type: Observational
- Planned participants: 60
- From 20 Feb 2022 to the primary completion date, 31 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Glucocorticoid Therapy
Other illness
- Autoimmune diseases
- Hepatitis B or C positive
- Active cancer history
- History of asthma
- History of COPD
Other
- Heavy alcohol use
- Active smoking history
- Taking Plavix or Coumadin
- Blood donation within past 2 months
- Taking antihistamine on regular basis
Who the study is looking for
- Undergoing gastric bypass surgery
- Confirmed AUROC F=0 or F\>2 liver fibrosis
- Age 30-70 years
- BMI greater than 40 kg/m2
- Negative pregnancy test (female only)
- Lab Values: Normal TSH
Age in the registry: 30 years to 70 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mayo Clinic in Arizona Coordinator of this site? Confirm its status | Scottsdale | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.