NCT04238299Active, not recruiting
Application of Functional Renal MRI to Improve Assessment of Chronic Kidney Disease
Source: ClinicalTrials.gov · Last updated 12 May 2026
Brief summary (registry, in English)
Research question: Can multiparametric renal Magnetic Resonance Imaging (MRI) provide structural and functional assessment of the kidneys to deliver prognostic information and guide treatment options in chronic kidney disease (CKD)? Aims and objectives: 1. To establish a multiparametric renal MRI protocol in CKD cohorts. 2. To use multiparametric MRI to characterise people with and without CKD progression. 3. To compare multiparametric renal MRI with 'gold-standard' renal biopsy to determine pathological processes of CKD progression that are detectable by MRI.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 486 (actual)
- First submitted
- 20 Jan 2020
- Start date
- 1 Jun 2021
- Primary completion date
- 28 Feb 2027
- Lead sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
- Diseases
- Chronic kidney disease
- NCT number
- NCT04238299
What you commit to
- Study type: Observational
- Participants enrolled: 486
- From 1 Jun 2021 to the primary completion date, 28 Feb 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Glomerulonephritis (GN) actively receiving immunosuppression, or within the preceding 90 days.
- Solid organ transplant
Other illness
- Autosomal dominant polycystic kidney disease (ADPKD)
Other
- Multiple myeloma (MM)
- Acute Kidney Injury (AKI) within the preceding 90 days
- Known single kidney
- Contraindications to MRI (e.g. permanent pacemaker, metallic foreign bodies, claustrophobia etc.)
Who the study is looking for
- Age 18-75 years
- CKD category G3-4 or CKD category G1-2 with overt albuminuria (urine ACR\>30mg/mmol)
- Capable of giving informed consent
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Royal Derby Hospital Coordinator of this site? Confirm its status | Derby | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.