NCT04240522Recruiting
Prospective Longitudinal Observational Research in Atopic Dermatitis
Prospective Longitudinal Observational Research Study to Investigate the Remission of Atopic Dermatitis and Associated Allergic Diseases
Source: ClinicalTrials.gov · Last updated 5 Feb 2026
Brief summary (registry, in English)
Atopic dermatitis (AD) is a frequent chronic relapsing inflammatory skin disorder, characterized by intensely itchy eczema. AD usually starts within the first 2 years of life. In 30 - 60% of children, inflammation spreads onto other body surfaces such as the gastrointestinal tract, the respiratory tract, and the conjunctives within a few years. This sequence is called atopic march. Atopic dermatitis and associated atopic diseases are more frequent in families, suggesting a genetic predisposition. However, the underlying factors such as genetic phenotype, environmental factors, or life style which cause or worsen an existing allergic disease are not understood yet. Affected people suffer from recurrent flares that result in significantly impaired quality. This study will collect clinical and laboratory data to elucidate immunotolerance and preventiv stategies with the aim to develop new and individual treatment options of atopic diseases.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 1000 (estimated)
- First submitted
- 20 Jan 2020
- Start date
- 4 Apr 2017
- Primary completion date
- 30 Mar 2031
- Lead sponsor
- University of Zurich
- Diseases
- Atopic dermatitis (eczema), Asthma
- NCT number
- NCT04240522
What you commit to
- Study type: Observational
- Planned participants: 1000
- From 4 Apr 2017 to the primary completion date, 30 Mar 2031
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- \- Unable to give consent or refusal to participate in the study
Who the study is looking for
- Age 0 - 85 years
- Diagnosis of AD and/or another disease of the atopic group (i.e. allergic rhinitis, allergic asthma, food allergy)
- The inclusion of patients in this study is independent from the current therapy. During the study all patients will be kept on a therapy that is medically indicated
- The inclusion criteria for healthy controls in this study are as follows:
- Age 0 - 85 years
- No diagnosis or history of allergic disease
- The inclusion of patients in this study is independent from the current therapy. During the study all patients will be kept on a therapy that is medically indicated
- Written consent will be obtained after detailed information of the study was given to the participant.
Age in the registry: 1 year to 85 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Allergy Unit, Dept. of Dermatology, Unviersity Hosptial of Zurich Coordinator of this site? Confirm its status | Zurich | Switzerland | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.