NCT04248894Completed
Impact of Interval Training on Sympathetic Hyperactivity and Vascular Function
The Impact of High-intensity Interval Training Versus Moderate Continuous Training on Neurovascular Control in Patients With Heart Failure
Source: ClinicalTrials.gov · Last updated 29 Apr 2026
Brief summary (registry, in English)
In this study, the investigators are testing the hypothesis that reduction in sympathetic activity would be greater following high-intensity interval training (HIIT) than moderate-intensity continuous training (MICT) and correspond with improvements in peripheral vascular function, and skeletal muscle function in patients with heart failure with reduced ejection fraction (HFrEF).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 35 (estimated)
- First submitted
- 23 Jan 2020
- Start date
- Jan 2015
- Primary completion date
- Apr 2021
- Lead sponsor
- University of Sao Paulo General Hospital
- Diseases
- Heart failure
- NCT number
- NCT04248894
What you commit to
- Study type: Interventional
- Planned participants: 35
- From Jan 2015 to the primary completion date, Apr 2021
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Myocardial infarction within three months
- Unstable angina
- Acute heart failure
- Pulmonary disease
- Chronic renal disease
- History of stroke
- History of smoking
Other
- Pacemaker
- Peripheral neuropathy
- Untreated hypo/hyperthyroidism
- Body mass index (BMI) \>30 kg/m2
Who the study is looking for
- Functional Class II to III of New York Heart Association
- Left ventricular ejection fraction ≤40%
- Peak oxygen uptake (V̇O2) \<20 ml•kg-1•min-1
Age in the registry: 30 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Heart Institute (InCor) Coordinator of this site? Confirm its status | São Paulo | Brazil | Unknown status |
| Heart Institute Coordinator of this site? Confirm its status | São Paulo | Brazil | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.