NCT04252235Completed
Home Air Purification for Eosinophilic COPD
A Randomized Controlled Trial of Home Air Purification for Eosinophilic COPD
Source: ClinicalTrials.gov · Last updated 21 Oct 2026
Brief summary (registry, in English)
This study evaluates the influence of home air purification on the lung health of adults with eosinophilic COPD. Half of the participants will receive real air purifiers (HEPA filters) and half will receive sham air purifiers.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 178 (actual)
- First submitted
- 30 Jan 2020
- Start date
- 15 Mar 2021
- Primary completion date
- 20 Jan 2026
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Diseases
- COPD
- NCT number
- NCT04252235
What you commit to
- Study type: Interventional
- Participants enrolled: 178
- From 15 Mar 2021 to the primary completion date, 20 Jan 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- End stage chronic disease with life expectancy \<2 years as determined by PI judgment
Other
- Inability to complete monthly questionnaires
- Inability to perform lung function testing
- Regularly using a portable HEPA air purifier in the home at time of enrollment
- Living in location other than home (e.g. long term care facility)
- Planning to change residence within the study period
Who the study is looking for
- Age of 40 years or more
- Physician diagnosis of COPD \[Global Initiative for Obstructive Lung Disease (GOLD) Stage II-IV disease with Forced Expiratory Volume (FEV1)/ Forced Vital Capacity (FVC) ≤70% and FEV1 (% predicted) \<80%\]
- Blood eosinophil count of \>=150 cells per μL at screening or in the previous year
- Former smoker with tobacco exposure of \>=10 pack-years
Age in the registry: 40 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Beth Israel Deaconess Medical Center Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.