NCT04253106Completed
Liquid Biopsies for the Personalized Management of Patients with Hereditary Diffuse Gastric Cancer
Liquid Biopsies (blood, Gastric Fluid) for the Personalized Management of Patients with Hereditary Diffuse Gastric Cancer: a Pilot Project
Source: ClinicalTrials.gov · Last updated 23 Sept 2024
Brief summary (registry, in English)
Activating somatic mutations and methylation profiles identified by liquid biopsies could identify CDH1 and CTNNA1 pathogenic variants carriers with invasive diffuse gastric cancer undetectable by upper G-I endoscopy.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 16 (actual)
- First submitted
- 31 Jan 2020
- Start date
- 26 Nov 2020
- Primary completion date
- 10 Apr 2024
- Lead sponsor
- Assistance Publique - Hôpitaux de Paris
- Diseases
- Gastric and esophageal cancer
- NCT number
- NCT04253106
What you commit to
- Study type: Interventional
- Participants enrolled: 16
- From 26 Nov 2020 to the primary completion date, 10 Apr 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with cancer being treated
- Patients with metastatic cancer
- Medical contraindication to general anesthesia or FOGD (bleeding disorder, pregnant women )
Other
- Patients under guardianship or curator
Who the study is looking for
- Case:
- Patient ≥ 18 years old
- CDH1 or CTNNA1 germline pathogenic variant.
- No history of diffuse gastric cancer.
- French social security.
- Ability to understand and willingness to sign a written informed consent document.
- Volunteers:
- Patients ≥ 18 years old
- Patients with no oncological history
- Patients with macroscopically normal oeso-gastroduodenal fibroscopy
- French social security.
- Ability to understand and willingness to sign a written informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hopital Pitie-Salpetriere Coordinator of this site? Confirm its status | Paris | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.