NCT04253275Completed
Identification of Biomarkers in Ischemic Stroke - Clinical Trial
Source: ClinicalTrials.gov · Last updated 4 Mar 2024
Brief summary (registry, in English)
The objective of the study is to determine RNA blood biomarker based on 9 genes already identified in experimental studies, whose expression would be significantly increased in patient with ischemic stroke compared to controls.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 61 (actual)
- First submitted
- 7 Jan 2020
- Start date
- 24 Nov 2020
- Primary completion date
- 6 Feb 2024
- Lead sponsor
- University Hospital, Brest
- Diseases
- Stroke
- NCT number
- NCT04253275
What you commit to
- Study type: Interventional
- Participants enrolled: 61
- From 24 Nov 2020 to the primary completion date, 6 Feb 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior stroke
- GROUP FOR ISCHEMIC STROKE :
- \- Patients with TIA and a negative cerebral CT or MRI
- GROUP FOR HEMORRAGIC STROKE :
Other illness
- Cerebral hemorrhage related to subarachnoid hemorrhage
- Post-traumatic hemorrhage
- Hemorrhagic transformation in patients with ischemic stroke
- GROUP FOR HEALTHY CONTROLS :
- \- Contraindication MRI
Other
- Not affiliated to social security
- Patient under legal protection or deprived of liberty by a judicial or administrative decision
- Patient whose follow-up will be impossible
Who the study is looking for
- For ischemic stroke :
- Age \> 18-year-old
- Ischemic stroke diagnosed on clinical presentation and cerebral imaging (CT or MRI imaging)
- Inclusion inferior to 6 hours from stroke onset
- Initial NIHSS score \> 0 at the time of clinical examination
- Patients with multimodal imaging either through MRI or CT perfusion and supra-aortic vessels and intra-cerebral vessels (Willis circle) imaging \<0
- Procedure of signed consent in situation of emergency : consent of the patient if he has the possibility to sign or his representative if he is present
- For hemorragic stroke :
- Age \> 18 year-old
- Hemorrhagic stroke diagnosed on clinical presentation and cerebral imaging (CT or MRI imaging)
- Inclusion inferior to 6 hours from stroke onset
- Initial NIHSS score \> 0 at the time of clinical examination
- Hemorrhagic patients are paired for age and sex with ischemic patients
- Procedure of signed consent in situation of emergency : consent of the patient if he has the possibility to sign or his representative if he is present
- For healthy controls :
- Age \> 18 year-old
- Stroke-free standardized questionnaire
- Initial NIHSS score = 0
- Rankin score = 0
- High risk cardiovascular subjects
- Controls are paired for age, sex and cardiovascular risk measured by a score (European Heart Score) with ischemic patients
Age in the registry: 18 years to 99 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHRU Brest Coordinator of this site? Confirm its status | Brest | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.