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NCT04255745Completed

The Impact of a Resistance Training Intervention on Blood Pressure Control in Older Adults With Sarcopenia

Source: ClinicalTrials.gov · Last updated 2 Jun 2026

Brief summary (registry, in English)

Current prevention and treatment of high blood pressure (BP) in sarcopenia, by non-pharmacological approaches remain limited and are far from optimal. This randomized control intervention pilot study will provide new evidence of the unexplored relationship between muscle strength and high BP in sarcopenia, and experimentally test the effects of an evidence-based progressive resistance training intervention on BP, while also examining reversibility to identify muscle strength as a non-pharmacological target for BP control in older sarcopenic adults.

Status (registry)
Completed
Study type
Interventional
Enrollment
77 (actual)
First submitted
31 Jan 2020
Start date
27 Jan 2020
Primary completion date
30 Jun 2024
Lead sponsor
University of Illinois Chicago
NCT number
NCT04255745

What you commit to

  • Study type: Interventional
  • Participants enrolled: 77
  • From 27 Jan 2020 to the primary completion date, 30 Jun 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Diagnosis of cancer (other than non-melanoma skin cancer) that is/was active or treated with radiation or chemotherapy within the past 5 years;

Other illness

  • Subjects who self-reported having a history of a cardiovascular disease event or physician diagnosed cardiovascular disease (heart attack, heart failure, congenital heart disease, peripheral vascular disease, coronary revascularization, or angina that required overnight hospitalization), cerebrovascular disease (stroke, transient ischemic attack)
  • Diagnosis or history of cognitive impairment (Dementia, Alzheimer's Disease) or bipolar or psychotic disorder or hospitalization for psychological or emotional problems within the last 2 years
  • Diagnosis of autoimmune diseases, such as (but not limited to) lupus, multiple sclerosis, advanced/severe rheumatoid arthritis that would preclude exercising safely
  • Current abuser of alcohol or usage of illicit drugs or history of alcohol or drug abuse

Other

  • Subjects with self-report of inability to walk at least ¼ mile or walk 400 meters in \<15 minutes without sitting
  • Subjects with orthopedic pathology or deformity that prevents exercising safely
  • Diagnosis of advanced or severe osteoporosis or orthopedic deformities that may prevent strength training exercise safely
  • Participants from the same household as those already enrolled in the study
  • Planning to move out of the area or take an extended vacation during the study period
  • Current or planned participation in in another structured program that overtly focuses on exercise
  • Currently enrolled or planning to enroll into another research study that would limit full participation in the study
  • Investigator discretion for clinical safety or protocol adherence reasons

Who the study is looking for

  • Adults (men and women) aged 60 years and older (any racial/ethnic background)
  • Demonstrates adequate cognitive function by the MoCA (education adjusted score of \>22 at screening)
  • Sedentary or low active adults (not active in strength training)
  • Resides in the Chicagoland Area
  • Able to walk/perform exercise without complete dependence on assisted device
  • Able and willing to enroll and provide written informed consent, i.e., to meet the time and data collection requirements of the study, be randomized to 1 of 2 treatment arms, follow through assignment during 3 months active period, participate in 1 follow-up visit at 12 months

Age in the registry: 60 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University of Illinois at Chicago
Coordinator of this site? Confirm its status
ChicagoUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.