NCT04262128Completed
Sedentary Behavior in Older Women With and Without Type 2 Diabetes
Prolonged Sedentary Behavior in Older Women With and Without Type 2 Diabetes: Knowledge, Engagement, and Relationship to Cardiometabolic Risk
Source: ClinicalTrials.gov · Last updated 30 May 2025
Brief summary (registry, in English)
Sedentary behavior has been linked to cardiovascular morbidity and mortality, and is particularly common in older adults with type 2 diabetes. The purpose of this observational, mixed-methods study is to better understand the relationship between prolonged sedentary behavior and cardiovascular and metabolic health in older women.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 28 (actual)
- First submitted
- 6 Feb 2020
- Start date
- 30 Apr 2020
- Primary completion date
- 11 Oct 2024
- Lead sponsor
- University of Colorado, Denver
- Diseases
- Type 2 diabetes
- NCT number
- NCT04262128
What you commit to
- Study type: Observational
- Participants enrolled: 28
- From 30 Apr 2020 to the primary completion date, 11 Oct 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of hormone replacement therapy (e.g., estrogen, progesterone, testosterone) (within the past 5 years)
- Taking insulin, thiazolidinediones (e.g., rosiglitazone), glucagon-like peptide-1 (GLP1) agonists (e.g., exenatide), dipeptidyl peptidase-4 (DPP4) inhibitors (e.g., sitagliptin) or any medication for the treatment of T2D other than those listed above in the inclusion criteria
Other illness
- Type 1 diabetes
- Uncontrolled hypertension at rest (systolic \>160 or diastolic \>110 mmHg)
- Obstructive pulmonary disease or asthma with a forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) ratio \<70% of predicted
- Any of the following conditions:
- Unstable angina
- Recent myocardial infarction, cardiac surgery, or vascular surgery (\<3 months)
- Heart failure
- Peripheral artery disease (based on report of symptomatic claudication or ankle brachial index testing)
- Hepatic or renal disease
- Severe arthritis or mobility impairment that would interfere with exercise testing
- Dementia or evidence of cognitive impairment (Mini-Cog score \< 3)
Lab values
- Control participants only - HbA1C ≥ 5.7%
- Use of beta blockers or centrally-acting calcium channel blockers (i.e., diltiazem, verapamil) due to potential blunting of cardiorespiratory fitness assessments
- Uncontrolled T2D (HbA1C \>9.0%)
- Anemia (tHb \<10 mg/dL)
Age
- Age \<60 or \>75 years
Other
- Male
- Current tobacco or marijuana use or nicotine use within the last year
- Engaging in \>150 minutes/week of moderate to vigorous physical activity (assessed via Low-Level Physical Activity Recall questionnaire)
Who the study is looking for
- Female
- Age 60-75 years
- Postmenopausal (self-reported)
- BMI between 25-40 kg/m2
- Participants with T2D:
- T2D confirmed via chart review
- T2D diet controlled or treated with the following acceptable medication treatments: metformin, sulfonylureas, glinides, or glucose absorption blockers
Age in the registry: 60 years to 75 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Colorado Anschutz Medical Campus Coordinator of this site? Confirm its status | Aurora | United States | Unknown status |
Related publications
- Prolonged Sedentary Behavior and Cardiometabolic Risk in Older Women With and Without Type 2 Diabetes: The SitWise Study.J Womens Health (Larchmt) · 2026 · PMID 42934948
This page is information, not medical advice. Discuss any trial with your doctor.