NCT04286282CompletedPhase 2
Neuroinflammation and Modulating Factors in Depression and HIV
Neuroinflammation and Modulating Factors in Depression and HIV: The Growth Study-Group Therapy in HIV for Depression IN Uganda
Source: ClinicalTrials.gov · Last updated 9 Jan 2025
Brief summary (registry, in English)
Determine if depression, which persists after depression treatment at 26 weeks, is associated with increased innate inflammation in a prospective cohort of HIV-infected Ugandans receiving SSRIs in which group psychotherapy is initiated.
- Status (registry)
- Completed
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 109 (actual)
- First submitted
- 24 Feb 2020
- Start date
- 1 Feb 2021
- Primary completion date
- 9 Nov 2023
- Lead sponsor
- University of Minnesota
- Diseases
- HIV
- NCT number
- NCT04286282
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 109
- From 1 Feb 2021 to the primary completion date, 9 Nov 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- \- No additional exclusion criteria
Who the study is looking for
- For the depressed patient arm,
- Newly-presenting clinic patients (\<3 months)
- Mild to Moderately-Severe Depressive Symptoms with PHQ-9 score \>5 but \<20
- Not suicidal (PHQ-9 question 9 score \>2)
- Not receiving antiretroviral therapy (ART) at screening
- Outpatient, not requiring hospitalization
- For the non-depressed patient arm,
- Newly-presenting clinic patients (\<3 months)
- Not suicidal (PHQ-9 question 9 score \>2)
- Not receiving antiretroviral therapy (ART) at screening
- Outpatient, not requiring hospitalization
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Infectious Diseases Institute Coordinator of this site? Confirm its status | Kampala | Uganda | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.