NCT04288323CompletedPhase 4
Gadolinium Contrast-enhanced Abbreviated MRI (AMRI) vs. Standard Ultrasound for Hepatocellular Carcinoma (HCC) Surveillance in Patients With Cirrhosis
Abbreviated MRI (AMRI) vs. Ultrasound for HCC Surveillance in Cirrhosis
Source: ClinicalTrials.gov · Last updated 12 Feb 2026
Brief summary (registry, in English)
This study compares gadolinium contrast-enhanced Abbreviated MRI (AMRI) to standard ultrasound for Hepatocellular Carcinoma (HCC) screening and surveillance in subjects with liver cirrhosis.
- Status (registry)
- Completed
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 79 (actual)
- First submitted
- 25 Feb 2020
- Start date
- Apr 2018
- Primary completion date
- Dec 2025
- Lead sponsor
- University of California, San Diego
- Diseases
- Liver and biliary tract cancer
- NCT number
- NCT04288323
What you commit to
- Study type: Interventional · Phase 4
- Participants enrolled: 79
- From Apr 2018 to the primary completion date, Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Clinical screening exam of the liver performed at UCSD within the prior 90 days to consent
Other illness
- History of any liver cancer
- Subject has known allergy to any gadolinium agent
Age
- \< 18 years of age
Other
- VA patient
- MRI contraindication(s)
- Subject knows that she is pregnant or states she trying to become pregnant
- Positive urine pregnancy test in woman of childbearing potential
- Nursing mother
- Does not meet UC San Diego Intravenous Contrast Media Guidelines for administration of Eovist\*
Who the study is looking for
- Subject has been fully informed and has personally signed and dated the written Informed Consent and Health Insurance Portability and Accountability Act (HIPAA) documents.
- Adult subjects of any gender and any ethnic group with liver cirrhosis of any etiology,
- Subject is able and willing to complete required research procedures (screening/enrollment, clinical evaluation, safety procedures, lab collection if needed, research AMRI exam, research US exam) and the three optional surveys (if subject opts in for that) within specified time windows, and is willing to allow the study team to review clinical data including but not limited to other clinical radiology reports and images.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of California San Diego Coordinator of this site? Confirm its status | La Jolla | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.