NCT04291131Completed
BRAIN, Symptoms, and Physical Activity in COPD
Effects of Chronic Pain, Dyspnea, and Physical Activity Promotion on Functional Connectivity of the Brain in COPD
Source: ClinicalTrials.gov · Last updated 15 Aug 2025
Brief summary (registry, in English)
Persons with COPD have both chronic musculoskeletal pain and dyspnea that require accurate diagnosis and treatment, ultimately to optimize functional status. The investigators propose to use advanced neuroimaging techniques to understand central mechanisms of chronic pain, dyspnea, and physical activity promotion in COPD. The investigators' novel proposal to correlate subjective symptoms (chronic pain and dyspnea) with an objective central biomarker (resting state functional connectivity) and examine their changes in response to a non-pharmacological, non-addictive physical activity intervention will personalize the care of Veterans with COPD.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 9 (actual)
- First submitted
- 20 Feb 2020
- Start date
- 1 Jul 2020
- Primary completion date
- 30 Jun 2024
- Lead sponsor
- VA Office of Research and Development
- Diseases
- COPD
- NCT number
- NCT04291131
What you commit to
- Study type: Observational
- Participants enrolled: 9
- From 1 Jul 2020 to the primary completion date, 30 Jun 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Known metal in body including:
- shrapnel
- surgical medical clips
- implants
- pacemakers
- metal-based tattoos
Other illness
- History of seizures
- Current diagnosis of bipolar disorder, schizophrenia, or psychotic disorder
- Cognitive disorder such as dementia
Other
- Female sex
- Claustrophobia
- Known brain lesion
Who the study is looking for
- Greater than or equal to 40 years of age
- Clinical diagnosis of COPD defined as either a ratio of FEV1 to forced vital capacity \< 0.70 or chest CT evidence of emphysema or prior documentation of FEV1/FVC ratio of \< 0.7 and clinical evidence of COPD (defined as 10 pack-year cigarette smoking history, dyspnea, or on bronchodilators)
- Will participate in a physical activity intervention or exercise program
- Competent to provide informed consent
- Willingness to make return visits and be available by telephone for duration of study
Age in the registry: 40 years to - · Sex: Male · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.