NCT04293523Completed
A 48-Month Study to Evaluate Long-Term Effectiveness of Elocta on Joint Health
A 48-Month, Multi-Centre, Observational Study to Evaluate Long-Term Effectiveness of Elocta on Joint Health
Source: ClinicalTrials.gov · Last updated 22 Sept 2026
Brief summary (registry, in English)
This is a 48-month observational, prospective, multicentre study. The overall aim of the study is to evaluate the long-term effectiveness of Elocta treatment on joint health in patients treated prophylactically with Elocta in a real-world setting.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 427 (actual)
- First submitted
- 20 Feb 2020
- Start date
- 30 Mar 2020
- Primary completion date
- 4 May 2026
- Lead sponsor
- Swedish Orphan Biovitrum
- Diseases
- Haemophilia
- NCT number
- NCT04293523
What you commit to
- Study type: Observational
- Participants enrolled: 427
- From 30 Mar 2020 to the primary completion date, 4 May 2026
- 53 sites in 14 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Enrolment in another concurrent clinical interventional study, or intake of an Investigational Medicinal Product (IMP), within three months prior to inclusion in this study
- Presence of factor VIII antibodies (inhibitors) (≥0.60 Bethesda Unit \[BU\]/mL) at the latest available inhibitor test
Who the study is looking for
- Provided signed and dated informed consent by the patient, or the patient's legally authorized representative(s) for patients under the legal age, before any study-related activities are undertaken. Assent should be obtained from paediatric patients according to local regulations
- Have a diagnosis of haemophilia A
- At enrolment on prophylactic treatment with Elocta, independent of participation in the study
Sex: All · Does not accept healthy volunteers
Sites (53)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Universitätsklinik für Hämatologie und Hämatologisches Zentrallabor Inselspital Coordinator of this site? Confirm its status | Bern | Switzerland | Unknown status |
| Service et Laboratoire central d'hématologie, Adults Coordinator of this site? Confirm its status | Lausanne | Switzerland | Unknown status |
| Zentrum für Labormedizin Coordinator of this site? Confirm its status | Sankt Gallen | Switzerland | Unknown status |
| Universitatsspital Zurich, Klinik fur Medizinische Onkologie und Hamatologie Coordinator of this site? Confirm its status | Zurich | Switzerland | Unknown status |
| University Hospital Brno Coordinator of this site? Confirm its status | Brno | Czechia | Unknown status |
| University Hospital Ostrava Coordinator of this site? Confirm its status | Ostrava | Czechia | Unknown status |
| Dept. of Pediatric Haematology and Oncology, University Hospital Motol Coordinator of this site? Confirm its status | Prague | Czechia | Unknown status |
| Charite Universitatsmedizin Berlin Campus Virchow Klinikum Coordinator of this site? Confirm its status | Berlin | Germany | Unknown status |
| Universitätsklinikum Bonn AöR, Institut für Experimentelle Hämatologie und Transfusionsmedizin Coordinator of this site? Confirm its status | Bonn | Germany | Unknown status |
| Universitätsklinikum Frankfurt - Klinik für Kinder- und Jugendmedizin Coordinator of this site? Confirm its status | Frankfurt | Germany | Unknown status |
| Hämostaseologie/Hämophiliezentrum, Medizinische Klinik 2 Institut für Transfusionsmedizin, Universitätsklinikum Coordinator of this site? Confirm its status | Frankfurt | Germany | Unknown status |
| Universitatsklinikum Hamburg-Eppendorf (UKE) Coordinator of this site? Confirm its status | Hamburg | Germany | Unknown status |
| Medizinische Hochschule Hannover Coordinator of this site? Confirm its status | Hanover | Germany | Unknown status |
| Werlhof-Institut für Hämostaseologie GmbH Coordinator of this site? Confirm its status | Hanover | Germany | Unknown status |
| SRH-Klinikum Heidelberg Coordinator of this site? Confirm its status | Heidelberg | Germany | Unknown status |
| HZRM Hämophilie-Zentrum Rhein Main Coordinator of this site? Confirm its status | Mörfelden-Walldorf | Germany | Unknown status |
| Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital am Universitätsklinikum München Coordinator of this site? Confirm its status | München | Germany | Unknown status |
| Lastehaigla, Tallinn (Tallinn Children´s Hospital) Coordinator of this site? Confirm its status | Tallinn | Estonia | Unknown status |
| The North Estonia Medical Centre Hematoloogiakeskus, Regionalhaigla Coordinator of this site? Confirm its status | Tallinn | Estonia | Unknown status |
| Hospital Vall d'Hebron Coordinator of this site? Confirm its status | Barcelona | Spain | Unknown status |
| Hospital de la Santa Creu i Sant Pau Coordinator of this site? Confirm its status | Barcelona | Spain | Unknown status |
| Sant Johan De Deu Coordinator of this site? Confirm its status | Barcelona | Spain | Unknown status |
| Hospital Universitario Cruces Coordinator of this site? Confirm its status | Cruces | Spain | Unknown status |
| Hospital Universitario Donostia Coordinator of this site? Confirm its status | Donostia / San Sebastian | Spain | Unknown status |
| Hospital Universitario Carlos Haya Coordinator of this site? Confirm its status | Málaga | Spain | Unknown status |
| Hospital Virgen de la Arrixaca Coordinator of this site? Confirm its status | Murcia | Spain | Unknown status |
| Complejo Hospitalario de Navarra Coordinator of this site? Confirm its status | Navarro | Spain | Unknown status |
| Hospital Universitario Central de Asturias (HUCA) Coordinator of this site? Confirm its status | Oviedo | Spain | Unknown status |
| Hospital Universitario Son Espases Coordinator of this site? Confirm its status | Palma de Mallorca | Spain | Unknown status |
| Hospital Universitario Virgen del Rocio Coordinator of this site? Confirm its status | Seville | Spain | Unknown status |
| Hospital Alvaro Cunqueiro Coordinator of this site? Confirm its status | Vigo | Spain | Unknown status |
| Helsinki University Central Hospital, New Children Hospital Coordinator of this site? Confirm its status | Helsinki | Finland | Unknown status |
| Turku University Central Hospital, Paediatric and adolescent haematology and oncology clinic Coordinator of this site? Confirm its status | Turku | Finland | Unknown status |
| East Kent Hospitals University NHS Foundation Trust, Kent Haemophilia and Thrombosis Centre, Kent and Canterbury Hospital Coordinator of this site? Confirm its status | Canterbury | United Kingdom | Unknown status |
| Great Ormond Street Hospital, Royal London Hospital for Integrated Medicine Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
| Ippokrateio Hospital Thessaloniki (adult department) Coordinator of this site? Confirm its status | Thessaloniki | Greece | Unknown status |
| Ippokrateio Hospital Thessaloniki (pediatric department) Coordinator of this site? Confirm its status | Thessaloniki | Greece | Unknown status |
| University of Bari Aldo Moro (Centro Emofilia Policlinico - Pediatria U.O.) Coordinator of this site? Confirm its status | Bari | Italy | Unknown status |
| AUSL Romagna Centro Emofilia U.O.C., Medicina Trasfusionale Dipartimento Patologia, Clinica Ospedale M. Bufalini Coordinator of this site? Confirm its status | Cesena | Italy | Unknown status |
| Giannina Gaslini Institute Coordinator of this site? Confirm its status | Genova | Italy | Unknown status |
| Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
| University Hospital of Parma, AOUP, Haemophilia Center Coordinator of this site? Confirm its status | Parma | Italy | Unknown status |
| Uo Malattie Emorragiche e Trombotiche Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Universitá Catolica del Sacro Coure Coordinator of this site? Confirm its status | Rome | Italy | Unknown status |
| Azienda Ospedaliera Città della Salute e della Scienza di Torino Regina Margherita Coordinator of this site? Confirm its status | Torino | Italy | Unknown status |
| University Medical Center Groningen (UMCG) Coordinator of this site? Confirm its status | Groningen | Netherlands | Unknown status |
| The Royal Hospital Coordinator of this site? Confirm its status | Muscat | Oman | Unknown status |
| Dr Suliman Al Habib Hospital Riyadh Coordinator of this site? Confirm its status | Riyadh | Saudi Arabia | Unknown status |
| King Faisal Specialist Hospital KFSH, Adults Coordinator of this site? Confirm its status | Riyadh | Saudi Arabia | Unknown status |
| King Faisal Specialised Hospital, KFSH Riyadh, Children Coordinator of this site? Confirm its status | Riyadh | Saudi Arabia | Unknown status |
| Riyadh Military Hospital (P.S.M.C) Coordinator of this site? Confirm its status | Riyadh | Saudi Arabia | Unknown status |
| Hematologimottagning Sahlgrenska Coordinator of this site? Confirm its status | Gothenburg | Sweden | Unknown status |
| Department of Haematology, Oncology and Radiation Physics, Skåne University Hospital Malmö Coordinator of this site? Confirm its status | Malmö | Sweden | Unknown status |
| University Medical Centre Ljubljana Division of Paediatrics Coordinator of this site? Confirm its status | Ljubljana | Slovenia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.