NCT04298034Active, not recruitingPhase 3
Preeclampsia Postpartum Antihypertensive Treatment
Randomized Controlled Trial for Postpartum Antihypertensive Treatment of Women With Preeclampsia
Source: ClinicalTrials.gov · Last updated 20 Jul 2026
Brief summary (registry, in English)
The goal of this study is to compare whether antihypertensive treatment in the postpartum period decreases postpartum hypertension and its associated maternal morbidity, including risk of readmission and healthcare utilization in comparison with no treatment. Women with preeclampsia diagnosed during the antepartum, intrapartum or postpartum period will be randomized to either initiate antihypertensive treatment or standard of care. We hypothesize that postpartum antihypertensive treatment of patients with preeclampsia will decrease risk of hospital readmission, healthcare utilization and the number of severe range blood pressures at postpartum follow-up visits.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 300 (estimated)
- First submitted
- 4 Mar 2020
- Start date
- Jul 2020
- Primary completion date
- Jun 2025
- Lead sponsor
- Medical College of Wisconsin
- Diseases
- High blood pressure
- NCT number
- NCT04298034
What you commit to
- Study type: Interventional · Phase 3
- Planned participants: 300
- From Jul 2020 to the primary completion date, Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Chronic hypertension with superimposed preeclampsia
Other
- Diagnosis of preeclampsia after discharge from delivery hospitalization
- Persistent severe range blood pressures after delivery requiring initiation of antihypertensive regimen by the care team
- \>50% of blood pressures in the postpartum period were normal (systolic less than 140 AND diastolic less than 90)
Who the study is looking for
- Age \>= 18 years old
- Immediately postpartum (delivered in previous 96 hours)
- Diagnosed with preeclampsia during pregnancy, labor or immediately postpartum
- \>30% of blood pressures in the postpartum period were elevated (systolic 140 or higher OR diastolic 90 or higher)
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical College of Wisconsin/ Froedtert Hospital Coordinator of this site? Confirm its status | Milwaukee | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.