NCT04302272Recruiting
STRIVE Post-Market Registry Study
The Spiration® Valve System (SVS) Post-Market Registry Study for Severe Emphysema
Source: ClinicalTrials.gov · Last updated 16 Oct 2026
Brief summary (registry, in English)
This is a single-arm, prospective, multi-center, Registry study to evaluate the long-term safety and effectiveness of the Spiration Valve System (SVS) for the treatment of severe emphysema in a post-market setting.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 150 (estimated)
- First submitted
- 24 Feb 2020
- Start date
- 9 Oct 2021
- Primary completion date
- Dec 2026
- Lead sponsor
- Olympus Corporation of the Americas
- Diseases
- COPD
- NCT number
- NCT04302272
What you commit to
- Study type: Observational
- Planned participants: 150
- From 9 Oct 2021 to the primary completion date, Dec 2026
- 16 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Subjects who are not appropriate for SVS therapy based upon the US FDA-approved IFU requirements.
Other
- Subjects who were withdrawn from this study for any reason will not be allowed to re-enroll.
- Subjects who have incomplete screening or baseline data.
Who the study is looking for
- Adult patients with shortness of breath and hyperinflation associated with severe emphysema and evidence of low collateral ventilation.
- Subjects must understand and voluntarily sign an informed consent form.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (16)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| AnMed Health Coordinator of this site? Confirm its status | Anderson | United States | Recruiting |
| University of Maryland Coordinator of this site? Confirm its status | Baltimore | United States | Recruiting |
| Beth Israel Decaconess Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
| University of Chicago Coordinator of this site? Confirm its status | Chicago | United States | Recruiting |
| Northwestern University, Division of Pulmonary and Critical Care Medicine Coordinator of this site? Confirm its status | Chicago | United States | Recruiting |
| University of Miami Coordinator of this site? Confirm its status | Coral Gables | United States | Recruiting |
| University of Texas, Southwestern Coordinator of this site? Confirm its status | Dallas | United States | Recruiting |
| Baylor Scott & White Research Institute Coordinator of this site? Confirm its status | Dallas | United States | Recruiting |
| Duke University Medical Center Coordinator of this site? Confirm its status | Durham | United States | Recruiting |
| Memorial Hospital at Gulfport Coordinator of this site? Confirm its status | Gulfport | United States | Recruiting |
| Penn State Milton S. Hershey Medical Center Coordinator of this site? Confirm its status | Hershey | United States | Recruiting |
| University of Texas Health Science Center at Houston Coordinator of this site? Confirm its status | Houston | United States | Recruiting |
| El Camino, Taft Center for Clinical Research Coordinator of this site? Confirm its status | Mountain View | United States | Recruiting |
| Temple University Coordinator of this site? Confirm its status | Philadelphia | United States | Recruiting |
| Dignity Health St Joseph's Hospital and Medical Center Coordinator of this site? Confirm its status | Phoenix | United States | Recruiting |
| LSU Health Shreveport Coordinator of this site? Confirm its status | Shreveport | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.