NCT04312269Recruiting
Combining MyoCI With Memory Reactivation to Improve Motor Recovery After Stroke
Source: ClinicalTrials.gov · Last updated 27 May 2026
Brief summary (registry, in English)
This study will examine the combination of myoelectric computer interface (MyoCI) training with targeted memory reactivation (TMR) in chronic stroke survivors. The study aims to determine whether this training-plus-sleep combination will generalize to improve arm motor function over an extended training protocol in stroke survivors.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 70 (estimated)
- First submitted
- 9 Mar 2020
- Start date
- 25 Feb 2020
- Primary completion date
- 30 Jan 2027
- Lead sponsor
- Northwestern University
- Diseases
- Stroke
- NCT number
- NCT04312269
What you commit to
- Study type: Interventional
- Planned participants: 70
- From 25 Feb 2020 to the primary completion date, 30 Jan 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Ferromagnetic implants that are MRI incompatible
Other illness
- Visual impairment (such as hemianopia) preventing full view of screen
- Anesthesia or neglect in the affected arm, or visual hemineglect (score of 2 on the NIH Stroke Scale Extinction and Inattention subtest)
Other
- Inability to follow instructions of the MyoCI task
- Participation in another study on the affected arm within 6 weeks of enrollment or any pharmacological study
- Inability to understand or follow commands in English due to aphasia or other reason
- Diffuse or multifocal infarcts in both hemispheres
- Substantial arm pain preventing participation for 90 minutes a day
- Spasticity treatment (pharmacological or Botox) within last 3 months
Who the study is looking for
- Age at enrollment is 21 or older
- Hemiparesis from first ever stroke affecting arm movement at least 6 months prior to screening
- Severe to moderate motor impairment (FMA-UE of 7-40)
- At least some voluntary shoulder and elbow muscle activation
Age in the registry: 21 years to 100 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Northwestern University Coordinator of this site? Confirm its status | Chicago | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.