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NCT04312399Recruiting

Hormone Replacement Trial Against ALzheimers' Disease

Source: ClinicalTrials.gov · Last updated 27 Jan 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

The influence of postmenopausal hormone treatment on dementia is not clear. Dysfunctions in the metabolism of amyloid in the disease of Alzheimer result in an elevated presence of degradation products in cerebrospinal fluid. The degradation products in blood will be analysed during the trial, to get better insight in menopause and the start of hormonal therapy. Postmenopausal women with and without history of breast cancer will be recruited for the trial.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
600 (estimated)
First submitted
8 Jan 2020
Start date
17 Apr 2018
Primary completion date
31 Dec 2027
Lead sponsor
University Hospital, Ghent
NCT number
NCT04312399

What you commit to

  • Study type: Interventional
  • Planned participants: 600
  • From 17 Apr 2018 to the primary completion date, 31 Dec 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Alcohol and/or drug abuse

Other illness

  • hypertension
  • medical history of psychiatric comorbidity
  • medical history of neurologic symptoms with cognitive symptoms

Other

  • Longer than 10 years in menopause
  • thyroid dysfunction

Who the study is looking for

  • postmenopausal women
  • 40 - 65 years

Age in the registry: 40 years to 65 years · Sex: Female · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Ghent university hospital
Coordinator of this site? Confirm its status
GhentBelgiumRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.