NCT04312399Recruiting
Hormone Replacement Trial Against ALzheimers' Disease
Source: ClinicalTrials.gov · Last updated 27 Jan 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The influence of postmenopausal hormone treatment on dementia is not clear. Dysfunctions in the metabolism of amyloid in the disease of Alzheimer result in an elevated presence of degradation products in cerebrospinal fluid. The degradation products in blood will be analysed during the trial, to get better insight in menopause and the start of hormonal therapy. Postmenopausal women with and without history of breast cancer will be recruited for the trial.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 600 (estimated)
- First submitted
- 8 Jan 2020
- Start date
- 17 Apr 2018
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- University Hospital, Ghent
- Diseases
- Alzheimer disease
- NCT number
- NCT04312399
What you commit to
- Study type: Interventional
- Planned participants: 600
- From 17 Apr 2018 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Alcohol and/or drug abuse
Other illness
- hypertension
- medical history of psychiatric comorbidity
- medical history of neurologic symptoms with cognitive symptoms
Other
- Longer than 10 years in menopause
- thyroid dysfunction
Who the study is looking for
- postmenopausal women
- 40 - 65 years
Age in the registry: 40 years to 65 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ghent university hospital Coordinator of this site? Confirm its status | Ghent | Belgium | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.