NCT04312802Completed
Cardiopulmonary Testing for Potential Pancreas Transplant Candidates
Measurement of Cardiopulmonary Exercise Capacity in Patients with Type 1 Diabetes Mellitus Approaching Simultaneous Kidney Pancreas Transplantation
Source: ClinicalTrials.gov · Last updated 22 Jan 2025
Brief summary (registry, in English)
Patients being assessed for Kidney Pancreas transplantation often have pre-existing co-morbid disease that contributes to structural cardiac and vascular disease. There is no consensus on optimal pre-listing cardiac assessment to reliably minimize risk of peri-operative cardiac events. Functional status using the cardio-pulmonary exercise test (CPET) has been used in cardiac and abdominal surgery, including abdominal aortic aneurysm (AAA) repair and kidney transplantation, but high risk patients with diabetes are often lacking from these studies. This study will investigate the correlation between function, measures using CPET and standard cardiac assessment, and determine the variation in usual measures of anaerobic threshold and VO2 max in this population.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 10 (actual)
- First submitted
- 16 Mar 2020
- Start date
- Mar 2018
- Primary completion date
- Sept 2024
- Lead sponsor
- Oxford University Hospitals NHS Trust
- Diseases
- Type 1 diabetes
- NCT number
- NCT04312802
What you commit to
- Study type: Observational
- Participants enrolled: 10
- From Mar 2018 to the primary completion date, Sept 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Participant unable to undergo CPET testing due to limitation on mobility or limb movement
Who the study is looking for
- Participant is willing and able to give informed consent
- Diagnosed with type 1 diabetes mellitus with estimated glomerular filtration rate (eGFR)\<20ml/min or on renal replacement therapy referred for simultaneous pancreas-kidney (SPK) transplant
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Churchill Hospital Coordinator of this site? Confirm its status | Oxford | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.