NCT04313114Active, not recruiting
The PRIME-CRC Trial to Promote CRC Screening in Rural Communities
Patient-Centered Reminders to Inform, Motivate, and Engage Colorectal Cancer Screening Adherence in Rural Communities: The PRIME-CRC Trial
Source: ClinicalTrials.gov · Last updated 28 Oct 2026
Brief summary (registry, in English)
The investigators will expand an existing, patient-centered, health literacy strategy to promote longer-term adherence to colorectal cancer (CRC) screening in resource-limited, rural health clinics via colonoscopy or annual fecal immunochemical test (FIT). In the proposed 2-arm study, both PRIME-CRC and enhanced usual care (control) will incorporate health literacy evidence-based practices for delivering CRC patient information and counseling to aid patient decision making for selecting FIT or colonoscopy, including simplified test instructions. In addition, the PRIME-CRC arm will use a "stepped care" approach for reminding patients on proper CRC screening preparation for scheduled colonoscopy or completion of annual FIT. Patients in the PRIME-CRC arm will receive frequent follow-up contact from their health care provider via audio-recorded, automated call or SMS text, based on patient preference.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 804 (actual)
- First submitted
- 16 Mar 2020
- Start date
- 20 Sept 2021
- Primary completion date
- 1 Mar 2026
- Lead sponsor
- Louisiana State University Health Sciences Center Shreveport
- Diseases
- Colorectal cancer
- NCT number
- NCT04313114
What you commit to
- Study type: Interventional
- Participants enrolled: 804
- From 20 Sept 2021 to the primary completion date, 1 Mar 2026
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- have a previous history of cancer other than non-melanoma skin cancer;
- have a documented or uncorrectable cognitive, hearing, or visual impairment;
Other
- are up-to-date with CRC screening according to USPSTF guidelines (FOBT in less than a year, sigmoidoscopy less than 5 years, or colonoscopy less than 10 years);
- a family history that requires a more complete history and possible colonoscopy because of their risk factor;
- are too ill to participate
Who the study is looking for
- have been a patient at one of the participating FQHCs with at least one prior visit in the past 12 months;
- age 45 to 75 (based on USPSTF guidelines);
- English-speaking.
Age in the registry: 45 years to 75 years · Sex: All · Accepts healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CommuniHealth (dba Morehouse Community Medical Centers, Inc.) Coordinator of this site? Confirm its status | Bastrop | United States | Unknown status |
| CommuniHealth (dba Morehouse Community Medical Centers, Inc.) Coordinator of this site? Confirm its status | Marion | United States | Unknown status |
| Tensas Community Health Centers Coordinator of this site? Confirm its status | Saint Joseph | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.