NCT04316676Completed
The MATCH Investigation: CT Myocardial Perfusion and CT-FFR vs PET MPI
MyocardiAl CT Perfusion and Coronary Flow: a CompreHensive Cardiac CT Myocardial Perfusion Imaging (MPI)/Fractional Flow Reserve (FFR) and PET-CT MPI Evaluation (The MATCH Investigation)
Source: ClinicalTrials.gov · Last updated 6 Jan 2026
Brief summary (registry, in English)
The overall goal of this project is to compare the absolute quantification of myocardial perfusion done by using CT myocardial perfusion imaging (CT-MPI) and the coronary flow measured by using CT Fractional Flow Reserve analysis (CT-FFR) to the gold standard represented by PET myocardial perfusion imaging (PET-MPI).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 20 (actual)
- First submitted
- 16 Mar 2020
- Start date
- 16 Jun 2021
- Primary completion date
- 24 Sept 2024
- Lead sponsor
- Emory University
- Diseases
- Coronary artery disease
- NCT number
- NCT04316676
What you commit to
- Study type: Interventional
- Participants enrolled: 20
- From 16 Jun 2021 to the primary completion date, 24 Sept 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Currently taking or has taken within 48 hours the following excluded medications:
- ActoPlus Met (Pioglitazone + metformin)
- Avandamet (Rosiglitazone + metformin)
- Fortamet (metformin)
- Glucovance (Glyburide +metformin)
- Glucophage (metformin)
- Glucophage extended-release (XR) (metformin)
- Glumetza (metformin)
- Janumet (Sitagliptin + metformin)
- Metformin
- Metaglip (Glipizide + metformin)
- Riomet (metformin)
- Previously entered this study
Other illness
- Acute psychiatric disorder
- Known hypersensitivity to iodinated contrast material, beta-blockers, or pharmaceutical stressors used in this study
Lab values
- Pregnant or nursing females. The possibility of pregnancy will be excluded by testing (serum or urine ßHCG) within 24 hours before study agent administration, or if the woman has previous surgical sterilization, or if the woman is post-menopausal, with minimum one (1) year history without menses.
- Impaired renal function (GFR \< 45 ml/min)
Other
- Unwilling to comply with the requirements of the protocol
- Suffers from claustrophobia
- Acute hypotension (\<100 mm Hg systolic)
- 2nd or 3rd degree atrioventricular (AV) block
Who the study is looking for
- Referred for a clinically indicated CT-MPI for CAD assessment
- Must provide written informed consent prior to any study-related procedures being performed
- Must be willing to comply with all clinical study procedures
Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Emory University Hospital Coordinator of this site? Confirm its status | Atlanta | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.