NCT04322461Completed
Effect of Exercise, Endocannabinoids and Ketones on Cerebral Metabolism in a Cognitive Disorders Population
Effect of Exercise, Endocannabinoids and Ketones on Cerebral Metabolism in a Cognitive Disorders Population : Pilot Project PARKA
Source: ClinicalTrials.gov · Last updated 3 Jun 2025
Brief summary (registry, in English)
A two months intervention in which two groups of cognitive disorders, Parkinson and Alzheimer's disease, will receive 50g/day of a commercial MCT supplement combined with supervised aerobic exercise 3 times/week. Cognition and ketones will be assess before and after the intervention, along with endocannabinoids plasma concentrations.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 14 (actual)
- First submitted
- 24 Mar 2020
- Start date
- 1 May 2022
- Primary completion date
- 27 May 2024
- Lead sponsor
- Université de Sherbrooke
- Diseases
- Alzheimer disease, Parkinson disease
- NCT number
- NCT04322461
What you commit to
- Study type: Interventional
- Participants enrolled: 14
- From 1 May 2022 to the primary completion date, 27 May 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Coconut allergy
- Cardiac disease
- Any uncontrolled disease that could interfer with the project.
Other
- MMSE \< 20
- MCT or coconut oil supplementation
- Cannabis, THC or CBD consumption
- Excessive alcohol consumption
- Physical activity 3x/week
- Presence of an metallic object in the body
- Impossibility to lay in dorsal decubitus for 40 minutes
Who the study is looking for
- Alzheimer's or parkinson disease diagnostic
- Stable medication associated with the disease
- Able to consent
- Presence of an accompanying person for the first and last visit.
- Ability to read and talk in French
Age in the registry: 60 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre de recherche sur le vieillissement Coordinator of this site? Confirm its status | Sherbrooke | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.