NCT04332536Completed
Limitations of Aerobic Capacity in Chronic Heart Failure
Role and Implications of Central Fatigue Limiting Aerobic Capacity in Chronic Heart Failure: The Head vs. Heart Study
Source: ClinicalTrials.gov · Last updated 26 Oct 2024
Brief summary (registry, in English)
This study will use a novel CPX test that incorporates instantaneous assessment of maximal isokinetic cycling power at V̇O2peak to elucidate the mechanisms that limit V̇O2peak in CHF, and compare these responses with age-matched controls.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 91 (actual)
- First submitted
- 27 Mar 2020
- Start date
- 1 Dec 2019
- Primary completion date
- 25 Aug 2024
- Lead sponsor
- University of Leeds
- Diseases
- Heart failure
- NCT number
- NCT04332536
What you commit to
- Study type: Interventional
- Participants enrolled: 91
- From 1 Dec 2019 to the primary completion date, 25 Aug 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Current diagnosis of cancer, inflammatory or musculoskeletal disease (e.g. rheumatoid arthritis), on-going infection or sepsis.
Lab values
- Co-morbidities: significant COPD (FEV1\<50%), severe renal disease (eGFR\<20) or primary pulmonary hypertension as a co-morbidity
Other
- Class IV CHF
- Any contraindications to exercise
- Unable to give informed consent
Who the study is looking for
- Patients with NYHA class I-III
- Stable CHF of at least 3 months duration
- On optimally tolerated medication for CHF
- No contraindications for cycling exercise
- Able to give informed consent
Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Leeds Teaching Hospitals NHS Trust Coordinator of this site? Confirm its status | Leeds | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.