NCT04359732Completed
Assessment of Response to nCRT for GEJ Cancer Using a Fully Integrated PET/MRI
Prediction of Assessment of Response to Neoadjuvant Chemo-Radio-Therapy (nCRT) for Esophageal and Gastroesophageal Junction Cancer (GEJ) Using a Fully Integrated PET/MRI
Source: ClinicalTrials.gov · Last updated 21 Sept 2026
Brief summary (registry, in English)
Evaluate the potential role of PET/MRI as a predictor of esophageal and junctional cancers in response to neoadjuvant chemoradiotherapy (nCRT).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 121 (actual)
- First submitted
- 20 Apr 2020
- Start date
- May 2020
- Primary completion date
- Feb 2026
- Lead sponsor
- IRCCS San Raffaele
- Diseases
- Gastric and esophageal cancer
- NCT number
- NCT04359732
What you commit to
- Study type: Interventional
- Participants enrolled: 121
- From May 2020 to the primary completion date, Feb 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- contraindications to preoperative imaging (such as pacemaker, allergy to contrast agents);
- contraindication to surgery (comorbidities, distant metastatic disease (imaging confirmed));
- severe hypersensitivity to gadobutrol or fludeoxyglucose F18.
Other
- \- incomplete preoperative imaging assessment;
- contraindications to neoadjuvant treatment;
- inability to complete imaging examinations (i.e. severe claustrophobia);
- pregnant or lactating women
Who the study is looking for
- biopsy-proven esophageal or junctional carcinomas (either adenocarcinoma (AC) or squamous cell carcinoma (SCC) for which an Ivor-Lewis transthoracic esophagectomy with supramesocolic and mediastinal lymphadenectomy is indicated;
- visible tumor on pre-treatment imaging;
- ≥ 18 years of age;
- signed informed consent.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Deaprtment of Radiology, IRCCS Ospedale San Raffaele Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.