NCT04364373Recruiting
D2 vs D3 Lymph Node Dissection for Left Colon Cancer
D2 vs D3 Lymph Node Dissection for Left Colon Cancer: Multicenter Randomize Control Trial (DILEMMA)
Source: ClinicalTrials.gov · Last updated 17 Aug 2026
Brief summary (registry, in English)
The efficiency of the D3 lymph node dissection is still controversial for left colon cancer patients. This study will try find difference in 5-year overall survival between D2 and D3 lymph node dissection. Investigation of the functional and short-term outcomes will clarify safety of the D3 lymph node dissection.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 1381 (estimated)
- First submitted
- 1 Apr 2020
- Start date
- 31 Mar 2020
- Primary completion date
- 31 Dec 2028
- Lead sponsor
- Russian Society of Colorectal Surgeons
- Diseases
- Colorectal cancer
- NCT number
- NCT04364373
What you commit to
- Study type: Interventional
- Planned participants: 1381
- From 31 Mar 2020 to the primary completion date, 31 Dec 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous radiotherapy or chemotherapy
Other illness
- Preoperative complications of the tumor (perforation and full bowel 3. obstruction)
Other
- сТis - Т2, сТ4b (tail of the pancreas, stomach, small bowel, ureter, urinary bladder)
- Synchronous or metachronous tumors
- Women during Pregnancy or breast feeding period
Who the study is looking for
- Agreement of the patient to participate in trial
- Colon cancer (only adenocarcinoma )
- The tumor located between the splenic flexure and rectosigmoid junction
- cT3-Т4а,b
- cN0-2
- cM0
- Tolerance of chemotherapy
- ASA 1-3
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Clinic of coloproctology and minimally invasive surgery Coordinator of this site? Confirm its status | Moscow | Russia | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.