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NCT04367805Active, not recruiting

COVID-19 Infection in Patients With Hepatocellular Carcinoma

Impact of COVID-19 Infection in Patients With Hepatocellular Carcinoma: An Ambispective Study Nestled in the CHIEF Cohort

Source: ClinicalTrials.gov · Last updated 15 Jun 2026

Brief summary (registry, in English)

Since December 2019, a new disease named COVID-19 linked to a new coronavirus, SARS-CoV2 has emerged in China in the city of Wuhan, Hubei province, spreading very quickly to all 5 continents, and responsible for a pandemic. France is the third most affected country in Europe after Italy and Spain. Groups of patients at a higher risk of developing a severe form of COVID-19 have been defined: this include patients with immunosuppressive disease as cancer or patients with advanced cirrhosis of the liver. Coronavirus liver injury had been described with SARS-CoV 1 and MERS-CoV. There is no data on liver damage associated with COVID-19 infection for compensated or decompensated cirrhotic patients. The objectives of this project are to estimate the incidence of COVID-19 in hepatocellular carcinoma population, both hospital and ambulatory, and to study the impact on the frequency of severe forms, the prognosis, but also liver function, and the management of hepatocellular carcinoma, in this context of pandemic

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
23 (actual)
First submitted
27 Apr 2020
Start date
22 May 2020
Primary completion date
1 Feb 2024
Lead sponsor
Centre Hospitalier Universitaire, Amiens
NCT number
NCT04367805

What you commit to

  • Study type: Observational
  • Participants enrolled: 23
  • From 22 May 2020 to the primary completion date, 1 Feb 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Other proven causes of pneumonia and absence of COVID-19

Other

  • Patient refusal
  • Influenza only, confirmed by a diagnostic test

Who the study is looking for

  • Patients with CHC and included in the French national prospective cohort CHIEF
  • Hospital and ambulatory patients
  • Infection confirmed by COVID-19 defined by a positive nasopharyngeal PCR or if PCR COVID-19 negative : CT showing COVID-19 compatible pneumonia
  • Suspected COVID-19 infection, not confirmed by COVID-19 PCR or chest CT, with no other known cause of acute pneumonia.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
CHU Amiens
Coordinator of this site? Confirm its status
AmiensFranceUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.