NCT04368702Recruiting
CONFIRM: Magnetic Resonance Guided Radiation Therapy
Clinical Onboard Utilization of Image Guided Radiation Therapy With Magnetic Resonance (CONFIRM): A Master Protocol
Source: ClinicalTrials.gov · Last updated 9 Feb 2026
Brief summary (registry, in English)
This research is being done to determine the safety and feasibility of using a type of radiation guided by magnetic resonance imaging (MRI) and chemotherapy to treat patients with gastric and breast cancer. The name of the radiation machine involved in this study is the MRIdian Linear Accelerator.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 70 (estimated)
- First submitted
- 22 Apr 2020
- Start date
- 1 May 2021
- Primary completion date
- 18 Jun 2029
- Lead sponsor
- Brigham and Women's Hospital
- NCT number
- NCT04368702
What you commit to
- Study type: Interventional
- Planned participants: 70
- From 1 May 2021 to the primary completion date, 18 Jun 2029
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of allergic reactions attributed to gadolinium-based IV contrast
- \-- Note: If patient will not receive contrast, this is not applicable and kidney function will not affect eligibility
- Any other exclusion criteria listed in the specific disease site cohort
Other
- Severe claustrophobia or anxiety
- Participants who cannot undergo an MRI
Who the study is looking for
- Participants must have histologically or cytologically confirmed malignancy requiring radiation
- Age 18 years of older
- ECOG performance status ≤2 (Karnofsky ≥60%, see Appendix A)
- Ability to understand and the willingness to sign a written informed consent document.
- Any further criteria listed in the specific disease site cohort
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Dana-Farber Cancer Institute Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
| Brigham & Women's Hospital Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.