NCT04380454Completed
Biomechanical and Neural Mechanisms of Post-stroke Gait Training
Source: ClinicalTrials.gov · Last updated 8 Sept 2026
Brief summary (registry, in English)
The study seeks to develop an understanding of how, why, and for whom fast treadmill walking (Fast) and Fast with functional electrical stimulation (FastFES) induce clinical benefits, allowing future development of cutting-edge, individually-tailored gait treatments that enhance both gait quality and gait function.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 55 (actual)
- First submitted
- 4 May 2020
- Start date
- 16 Mar 2021
- Primary completion date
- 1 Oct 2025
- Lead sponsor
- Emory University
- Diseases
- Stroke
- NCT number
- NCT04380454
What you commit to
- Study type: Interventional
- Participants enrolled: 55
- From 16 Mar 2021 to the primary completion date, 1 Oct 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- hemorrhagic stroke
- score of \>1 on question 1b and \>0 on question 1c on NIH Stroke Scale
- musculoskeletal conditions or pain that limit walking
- neurologic conditions or diagnoses other than stroke
- lack of sensation in lower limb affected by stroke
- diabetes not controlled by medication or causing risk for participation in exercise programs
- additional exclusion criteria due to contra-indications to TMS (measurement of corticospinal excitability) are: history of seizures, metal implants in the head or face, history of recurring or severe headaches/migraine, headache within the past 24 hours, presence of skull abnormalities or fractures, hemorrhagic stroke, history of dizziness, syncope, nausea, or loss of consciousness in the past 6 months
Other
- cerebellar signs (ataxic ("drunken") gait or decreased coordination during rapid alternating hand or foot movements
- inability to communicate with investigators
- neglect/hemianopia, or unexplained dizziness in last 6 months
- any medical diagnosis that would hinder the participant from completing the experimental trial
Who the study is looking for
- at least 6 months since stroke
- single cortical or subcortical ischemic stroke
- able to walk 10-meters with or without assistive device
- sufficient cardiovascular health and ankle stability to walk on treadmill for 2-minutes at self-selected speed without orthosis
- resting heart rate 40-100 bpm
Age in the registry: 35 years to 90 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Emory University Hospital Coordinator of this site? Confirm its status | Atlanta | United States | Unknown status |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.